5'-O-Trityl riboflavin

Base Information

• Chemical Name: 5'-O-Trityl riboflavin
• CAS No.: 136738-76-6
• Molecular Formula: C₃₆H₃₄N₄O₆
• Molecular Weight: 618.689
• Mol file: 136738-76-6.mol

Synonyms:5'-O-Trityl riboflavin

Chemical Property of 5'-O-Trityl riboflavin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-Trityl riboflavin

There total 2 articles about 5'-O-Trityl riboflavin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

trityl chloride (76-83-5) + riboflavin (83-88-5,42880-33-1) → 5'-O-Trityl riboflavin (136738-76-6)

Guidance literature:

With pyridine; at 110 ℃; for 1h;

DOI:10.1016/S0040-4039(00)94611-2

Reference yield:

trityl chloride (76-83-5) + arabinoflavin (33210-89-8,42880-33-1) → 7,8-dimethyl-10-(O5-trityl-L-arabitol-1-yl)-10H-benzo[g]pteridine-2,4-dione (136738-76-6)

Guidance literature:

With pyridine;

Reference yield: 100.0%

5'-O-Trityl riboflavin (136738-76-6) + p-Anisaldehyde dimethyl acetal (2186-92-7) → 2',4'-O-p-Methoxybenzylidene 5'-O-trityl-riboflavin (127877-16-1)

Guidance literature:

With pyridinium p-toluenesulfonate; In N,N-dimethyl-formamide; for 4h; Ambient temperature;

DOI:10.1016/S0040-4020(01)86553-4

upstream raw materials:

trityl chloride

arabinoflavin

riboflavin

Downstream raw materials:

2',4'-O-p-Methoxybenzylidene 5'-O-trityl-riboflavin

2',4'-O-p-Methoxybenzylidene riboflavin

10-[(4S,5S,6R)-5-Hydroxy-6-[(3aR,4R,6R,6aR)-6-hydroxymethyl-2-(4-methoxy-phenyl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-yloxymethyl]-2-(4-methoxy-phenyl)-[1,3]dioxan-4-ylmethyl]-7,8-dimethyl-10H-benzo[g]pteridine-2,4-dione

10-[(4S,5S,6R)-5-Hydroxy-6-[(3aR,4S,6R,6aR)-6-hydroxymethyl-2-(4-methoxy-phenyl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-yloxymethyl]-2-(4-methoxy-phenyl)-[1,3]dioxan-4-ylmethyl]-7,8-dimethyl-10H-benzo[g]pteridine-2,4-dione

Refernces

• 1、 Isobe, Minoru,Takahashi, Hiroyuki,Goto, Toshio. "Lampteromyces bioluminescence - 5 Chemical synthesis of lampteroflavin as mushroom light emitter". . p. 717 - 718. Retrieved 2007/10/02.