6-Chloro-2-iodo-3-hydroxypyridine

Base Information

Chemical Name:6-Chloro-2-iodo-3-hydroxypyridine
CAS No.:188057-26-3
Molecular Formula:C5H3ClINO
Molecular Weight:255.442
Hs Code.:2933399090
Mol file:188057-26-3.mol

Synonyms:3-Hydroxy-6-chloro-2-iodopyridine;6-Chloro-2-iodo-3-hydroxypyridine;

Suppliers and Price of 6-Chloro-2-iodo-3-hydroxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-2-iodopyridin-3-ol
100mg
$ 60.00

TCI Chemical
6-Chloro-2-iodo-3-hydroxypyridine >98.0%(GC)(T)
5g
$ 174.00

TCI Chemical
6-Chloro-2-iodo-3-hydroxypyridine >98.0%(GC)(T)
1g
$ 58.00

Crysdot
6-Chloro-2-iodopyridin-3-ol 98%
5g
$ 138.00

Chem-Impex
6-Chloro-2-iodo-3-hydroxypyridine,≥98%(GC) ≥98%(GC)
1G
$ 68.52

Chemenu
6-Chloro-2-iodopyridin-3-ol 98%
5g
$ 143.00

Chemenu
6-Chloro-2-iodopyridin-3-ol 98%
10g
$ 221.00

Chemcia Scientific
6-Chloro-2-iodo-pyridin-3-ol 97%
10 G
$ 190.00

AOBChem
6-Chloro-2-iodo-3-hydroxypyridine 97%
25g
$ 369.00

American Custom Chemicals Corporation
6-CHLORO-2-IODO-3-HYDROXYPYRIDINE 95.00%
1G
$ 655.49

Total 47 raw suppliers

Chemical Property of 6-Chloro-2-iodo-3-hydroxypyridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:191-193℃
Refractive Index:1.691
Boiling Point:332.821 °C at 760 mmHg
PKA:4.22±0.10(Predicted)
Flash Point:155.085 °C
PSA：33.12000
Density:2.219 g/cm³
LogP:2.04520
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Light Sensitive
Solubility.:Slightly Soluble (1.3 g/L) (25°C).

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloro-2-iodopyridin-3-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2,2'-Dipyridylamine has been obtained by by heating a mixture of 2-aminopyridine and 2-bromo- (chloro-, iodo- ) -pyridine with anhydrous zinc chloride or with barium oxide.

Technology Process of 6-Chloro-2-iodo-3-hydroxypyridine

There total 4 articles about 6-Chloro-2-iodo-3-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 41288-96-4
6-chloropyridine-3-ol

: 188057-26-3
6-chloro-2-iodopyridine-3-ol

Guidance literature:: With iodine; sodium hydrogencarbonate; In water;
DOI:10.1016/j.ejmech.2021.113299

Reference yield:

: 41288-96-4
6-chloropyridine-3-ol

: 497-19-8
sodium carbonate

: 188057-26-3
6-chloro-2-iodopyridine-3-ol

Guidance literature:: With I₂; In water;

Reference yield:

: 5350-93-6
6-Chloro-pyridin-3-ylamine

: 188057-26-3
6-chloro-2-iodopyridine-3-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: BF₃*Et₂O; i-BuONO / 1,2-dimethoxy-ethane; CH₂Cl₂ / 0 °C

1.2: 62 percent / 75 °C

2.1: 94 percent / K₂CO₃ / methanol / 20 °C

3.1: 95 percent / I₂; Na₂CO₃ / H₂O

With nitrous acid isobutyl ester; boron trifluoride diethyl etherate; iodine; sodium carbonate; potassium carbonate; In methanol; 1,2-dimethoxyethane; dichloromethane; water;
DOI:10.1016/S0040-4039(02)02655-2