4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride

Base Information

• Chemical Name: 4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride
• CAS No.: 1610892-98-2
• Molecular Formula: C₁₁H₁₇N₃O₃S*ClH
• Molecular Weight: 307.801
• Mol file: 1610892-98-2.mol

Synonyms:4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride

Chemical Property of 4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride

There total 1 articles about 4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-homosulfanilamide (138-39-6) → 4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride (1610892-98-2)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 65 h / 0 - 20 °C

2: hydrogenchloride / 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;

DOI:10.1016/j.bmcl.2014.06.024

Reference yield: 70.0%

4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride (1610892-98-2) + phenyl isocyanate (103-71-9) → 4-(3-phenylureido)-N-(4-sulfamoylbenzyl)butanamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2014.10.041

Reference yield: 69.0%

4-oxo-4-((4-sulfamoylbenzyl)amino)butan-1-aminium chloride (1610892-98-2) + 1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine (207857-15-6) → N,N′-di-Boc-guanidino-N″-(4-sulfamoyl-benzyl)-butyramide (1610893-00-9)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃;

DOI:10.1016/j.bmcl.2014.06.024

upstream raw materials:

4-homosulfanilamide

Downstream raw materials:

4-guanidino-N-(4-sulfamoyl-benzyl)-butyramide hydrochloride

N,N′-di-Boc-guanidino-N″-(4-sulfamoyl-benzyl)-butyramide