N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide

Base Information

• Chemical Name: N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide
• CAS No.: 294867-69-9
• Molecular Formula: C₂₅H₃₂N₂O₆
• Molecular Weight: 456.539

Synonyms:N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide

Chemical Property of N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide

There total 2 articles about N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,2-dimethoxy-propane (77-76-9) + N1,N6-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy hexanediamide (294867-67-7) → N1,N6-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide (294867-69-9)

Guidance literature:

With camphor-10-sulfonic acid; In acetone; for 0.25h;

DOI:10.1139/v00-012

Reference yield:

2,5-di-O-benzyl-L-mannaro-1,4:3,6-di-γ-lactone (213895-58-0) → N1,N6-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide (294867-69-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / 2-hydroxypyridine / tetrahydrofuran; CHCl₃ / 0.25 h / 20 °C

2: 85 percent / camphorsulfonic acid / acetone / 0.25 h

With 2-hydroxypyridin; camphor-10-sulfonic acid; In tetrahydrofuran; chloroform; acetone; 1: Ring cleavage / 2: Condensation;

DOI:10.1139/v00-012

Reference yield:

N1,N6-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide (294867-69-9) → N1,N6-dimethyl-N1,N6-dinitroso-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide

Guidance literature:

With lead(II) nitrate; sodium acetate; dinitrogen tetraoxide; In dichloromethane; at -60 - -10 ℃; for 1.5h;

DOI:10.1139/v00-012

upstream raw materials:

2,2-dimethoxy-propane

N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy hexanediamide

2,5-di-O-benzyl-L-mannaro-1,4:3,6-di-γ-lactone

Downstream raw materials:

2,5-di-O-benzyl-3,4-O-isopropylidene-L-mannaric acid

N₁,N₆-disuccinimidyl-(2R,3R,4R,5R)-2,5-di(benzyloxy)-3,4-O-isopropylidenehexanediamide

BEA₃₈₈

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 294867-69-9 N₁,N₆-dimethyl-(2R,3R,4R,5R)-2,5-dibenzyloxy-3,4-dihydroxy-3,4-O-isopropylidenehexanediamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send