(1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

Base Information

Chemical Name:(1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester
CAS No.:198022-67-2
Molecular Formula:C₁₆H₁₈O₄
Molecular Weight:274.317
Hs Code.:

Synonyms:(1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

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Chemical Property of (1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

Chemical Property:

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Technology Process of (1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

There total 3 articles about (1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35878-28-5,743438-34-8
cyclopentane-cis-1,2-dicarboxylic acid anhydride

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

: 198022-67-2
(1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

Guidance literature:: With Quinine; In toluene; at -15 ℃;
DOI:10.1016/S0960-894X(02)00958-7

Reference yield:

: 50483-99-3
trans-DL-1,2-cyclopentanedicarboxylic acid

: 198022-67-2
(1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

Guidance literature:: Multi-step reaction with 2 steps

1: (EtCO)2O / 135 °C

2: quinine / toluene / -15 °C

With propionic acid anhydride; Quinine; In toluene;
DOI:10.1016/S0960-894X(02)00958-7

Reference yield:

: 90474-13-8
diethyl cyclopentane-1,2-dicarboxylate

: 198022-67-2
(1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester

Guidance literature:: Multi-step reaction with 3 steps

1: aq. KOH / tetrahydrofuran

2: (EtCO)2O / 135 °C

3: quinine / toluene / -15 °C

With potassium hydroxide; propionic acid anhydride; Quinine; In tetrahydrofuran; toluene;
DOI:10.1016/S0960-894X(02)00958-7