50483-99-3

Usage

Uses

Used in Chemical Synthesis:
1,2-Cyclopentanedicarboxylic acid is used as an intermediate in the synthesis of trans-1,2-Dimethylcyclopentane (D464925) for [application reason] its role in the production of this specific hydrocarbon.
Used in Geological Studies:
In the field of geology, 1,2-Cyclopentanedicarboxylic acid is used as a chemical marker for [application reason] determining the maturation history of sedimentary rocks, as trans-1,2-Dimethylcyclopentane, which it helps synthesize, is one of the hydrocarbons found in these rocks.

Upstream product

• 30132-23-1 ethyl 3-bromo-2-oxocyclohexanecarboxylate 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 111-16-0 heptanedioic acid 
• 142-79-0 pimeloyl chloride 
• 90474-13-8 diethyl cyclopentane-1,2-dicarboxylate 
• 55623-59-1 di-tert-butyl pimelate 

Downstream Products

• 35878-28-5 cyclopentane-cis-1,2-dicarboxylic acid anhydride 
• 822-50-4 1,2-dimethylcyclopentane 
• 5763-44-0 4,5,6,6a-tetrahydro-3aH-cyclopenta[c]pyrrole-1,3-dione 
• 3145-88-8 Cyclopentan-1.2-trans-diamin 
• 82442-56-6 trans-1,2-bis(hydroxymethyl)cyclopentane 
• 75658-83-2 cis-1,2-bis(hydroxymethyl)cyclopentane 
• 4841-91-2 dimethyl cis-1,2-cyclopentanedicarboxylate 
• 80656-12-8 dimethyl trans-cyclopentane-1,2-dicarboxylate 
• 198022-67-2 (1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester 

Relevant academic research and scientific papers

Method for synthesizing cyclopentyl imide

The invention relates to a method for synthesizing cyclopentyl imide. The method comprises the following steps: reacting a raw material 1,2-cyclopentanediamide with an alkali liquid to generate 1,2-cyclopentanediacid, and reacting the 1,2-cyclopentanediacid with methanamide to generate the cyclopentyl imide. The synthesis method greatly reduces the cyclopentyl imide synthesis temperature to make the reaction mildly proceed, so the high temperature problem in the prior art is solved, the safety in the production process is improved, and energy saving and consumption reduction are realized; and the method has the advantages of liquid and homogenous synthesis system, stable reaction and quality, low temperature reaction conditions, no generation of coking, oxidation or carbonizing waste resides or other impurities, improvement of the quality of the above product, realization of the continuous primary yield reaching 90% or above and being about 10-30% higher than that of present technologies, stable reaction technology conditions, easiness in control, and high reaction conversion rate.

Novel antifungal β-amino acids: Synthesis and activity against Candida albicans

A series of novel β-amino acids has been synthesized and tested for their in vitro antifungal activity against Candida albicans. A steep SAR was observed. β-Amino acid 21 (BAY 10-8888/PLD-118) revealed the most favourable activity-tolerability profile and was selected for clinical studies as a novel antifungal for the oral treatment of yeast infections.

A CYCLOPENTANE, CYCLOPENTENE AND CYCLOPENTANONE ANNULATION METHODOLOGY

The chemistry derived from the dienolates of 1,2-dicarboxylic acid esters is described.New methods for preparing cyclopentane, cyclopentene and cyclopentanone rings affixed to the diesters are discussed.