selenothiobenzoic acid Se-methyl ester

Base Information

• Chemical Name: selenothiobenzoic acid Se-methyl ester
• CAS No.: 136970-32-6
• Molecular Formula: C₈H₈SSe
• Molecular Weight: 215.178
• Mol file: 136970-32-6.mol

Synonyms:selenothiobenzoic acid Se-methyl ester

Chemical Property of selenothiobenzoic acid Se-methyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of selenothiobenzoic acid Se-methyl ester

There total 5 articles about selenothiobenzoic acid Se-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methyl thiobenzoate (5873-86-9) + dimethyl aluminum selenide (67132-62-1) → selenothiobenzoic acid Se-methyl ester (136970-32-6)

Guidance literature:

In diethyl ether; toluene; for 10h; Ambient temperature;

DOI:10.1039/c39910000964

Reference yield: 77.0%

tetrabutylammonium selenothiobenzoate + methyl iodide (74-88-4) → selenothiobenzoic acid Se-methyl ester (136970-32-6)

Guidance literature:

In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1021/ja000530v

Reference yield:

selenobenzoic acid O-methyl ester (5925-76-8) → selenothiobenzoic acid Se-methyl ester (136970-32-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trimethylaluminum / toluene / 1 h / -78 °C

1.2: 82 percent / toluene / 3 h / 20 °C

2.1: tetrahydrofuran / 3 h / 0 °C

3.1: 77 percent / tetrahydrofuran / 1 h / 0 °C

With trimethylaluminum; In tetrahydrofuran; toluene;

DOI:10.1021/ja000530v

upstream raw materials:

methyl thiobenzoate

dimethyl aluminum selenide

methyl iodide

selenobenzoic acid O-methyl ester

Downstream raw materials:

dimethyl diselenide

N,N-dimethylthiobenzamide

Refernces

• 1、 Khalid, Mohamed,Ripoll, Jean-Louis,Vallee, Yannick. "The First Synthesis of Se-Methyl Carboxylic Thionoselenolesters". . p. 964 - 965. Retrieved 2007/10/02.