C₂₅H₁₉FN₄O

Base Information

• Chemical Name: C₂₅H₁₉FN₄O
• CAS No.: 1007346-45-3
• Molecular Formula: C₂₅H₁₉FN₄O
• Molecular Weight: 410.45
• Mol file: 1007346-45-3.mol

Synonyms:C₂₅H₁₉FN₄O

Chemical Property of C₂₅H₁₉FN₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of C₂₅H₁₉FN₄O

There total 1 articles about C₂₅H₁₉FN₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(6-bromo-7-fluoro-3-methylindazol-1-yl)benzonitrile (1007346-41-9) + 1-[4-(4,4,5,5-tetramethyl-[1 ,3,2]dioxaborolan-2-yl)phenyl]pyrrolidin-2-one (1003309-09-8) → C25H19FN4O (1007346-45-3)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; toluene; at 100 ℃; for 18h;

DOI:10.1021/jm701217r

Reference yield:

C25H19FN4O (1007346-45-3) → 1-{4-[1-(3-aminomethyl-phenyl)-7-fluoro-3-methyl-1H-indazol-6-yl]-phenyl}-pyrrolidin-2-one

Guidance literature:

With hydrogen; nickel; In ethanol; at 20 ℃; for 18h; under 2585.81 Torr;

DOI:10.1021/jm701217r

upstream raw materials:

3-(6-bromo-7-fluoro-3-methylindazol-1-yl)benzonitrile

1-[4-(4,4,5,5-tetramethyl-[1 ,3,2]dioxaborolan-2-yl)phenyl]pyrrolidin-2-one

Refernces