N2-[2(R)-(N-Formyl-N-hydroxyaminomethyl)hexanoyl]-N1,N1-dimethyl-L-tert-leucinamide

Base Information

• Chemical Name: N2-[2(R)-(N-Formyl-N-hydroxyaminomethyl)hexanoyl]-N1,N1-dimethyl-L-tert-leucinamide
• CAS No.: 235784-88-0
• Molecular Formula: C₁₆H₃₁N₃O₄
• Molecular Weight: 329.44
• Mol file: 235784-88-0.mol

Synonyms:BB3497

Chemical Property of N2-[2(R)-(N-Formyl-N-hydroxyaminomethyl)hexanoyl]-N1,N1-dimethyl-L-tert-leucinamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.077g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N2-[2(R)-(N-Formyl-N-hydroxyaminomethyl)hexanoyl]-N1,N1-dimethyl-L-tert-leucinamide

There total 6 articles about N2-[2(R)-(N-Formyl-N-hydroxyaminomethyl)hexanoyl]-N1,N1-dimethyl-L-tert-leucinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-2-[(Benzyloxy-formyl-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide (235786-03-5) → BB 3497 (235784-88-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0960-894X(01)00509-1

Reference yield:

2-butylacrylic acid (4380-88-5) → BB 3497 (235784-88-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 °C

2: 100 percent / H₂ / Pd/C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0960-894X(01)00509-1

Reference yield:

n-butylmalonic acid (534-59-8) → BB 3497 (235784-88-0)

Guidance literature:

Multi-step reaction with 4 steps

1: piperidine / ethanol / 80 °C

2: 80 °C

3: 100 percent / H₂ / Pd/C / ethanol

With piperidine; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0960-894X(01)00509-1

upstream raw materials:

(R)-2-[(Benzyloxy-formyl-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide

2-butylacrylic acid

n-butylmalonic acid

2(R)-(N-benzyloxyamino-methyl)-hexanoic acid