4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine

Base Information

Chemical Name:4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine
CAS No.:186895-85-2
Molecular Formula:C16H19 N5
Molecular Weight:281.36
Hs Code.:
Mol file:186895-85-2.mol

Synonyms:1-(1,1-Dimethylethyl)-3-(phenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1-B-PP1;4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine

Suppliers and Price of 4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
10mg
$ 446.00

TRC
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
100mg
$ 1080.00

Medical Isotopes, Inc.
4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine
50 mg
$ 1960.00

Biosynth Carbosynth
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
50 mg
$ 841.50

Biosynth Carbosynth
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
25 mg
$ 463.00

Biosynth Carbosynth
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
10 mg
$ 254.50

Biosynth Carbosynth
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
5 mg
$ 140.00

Biosynth Carbosynth
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
100 mg
$ 1529.00

AK Scientific
3-Benzyl-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine
100mg
$ 2114.00

AK Scientific
3-Benzyl-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine
50mg
$ 1186.00

Total 7 raw suppliers

Chemical Property of 4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine

Chemical Property:

Melting Point:137-139°C
PSA：69.62000
LogP:3.33550
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly, Sonicated), Ethyl Acetate (Slightly), Methanol (Slightly, Sonica

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A derivative of 4-aminopyrazolo[3,4-d]pyridine as tyrosine kinase inhibitor.

Technology Process of 4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine

There total 5 articles about 4-Amino-1-tert-butyl-3-(3-benzyl)pyrazolo[3,4-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1-tert-butyl-3-phenylmethyl-5-amino-1H-pyrazole-4-carbonitrile

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 186895-85-2
3-benzyl-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Guidance literature:: at 150 ℃;
DOI:10.1039/c6md00675b

Reference yield:

: 1151649-93-2
(4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]-pyrimidin-3-yl)-phenyl-methanol

: 186895-85-2
3-benzyl-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Guidance literature:: With triethylsilane; trifluoroacetic acid; at 0 ℃;

Reference yield:

: 103-80-0
phenylacetyl chloride

: 186895-85-2
3-benzyl-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydride / tetrahydrofuran

2: sodium hydrogencarbonate / water; 1,4-dioxane

3: triethylamine / ethanol

4: 150 °C

With sodium hydride; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; 1,4-dioxane; ethanol; water;
DOI:10.1039/c6md00675b