7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Base Information

• Chemical Name: 7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
• CAS No.: 75001-53-5
• Molecular Formula: C₁₂H₉Cl₂NO₃
• Molecular Weight: 286.114
• Hs Code.: 2933499090
• Mol file: 75001-53-5.mol

Synonyms:ethyl 7,8-dichloro-4-hydroxyquinoline-3-carboxylate

Chemical Property of 7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 5.63E-07mmHg at 25°C
• Melting Point: 288-290 °C
• Boiling Point: 398.4±37.0 °C(Predicted)
• PKA: 5.13±0.50(Predicted)
• Density: 1.478±0.06 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

ETHYL 7,8-DICHLORO-4-HYDROXY-3-QUINOLINECARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

There total 10 articles about 7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-Dichlor-anilinomethylen-malonsaeure-diethylester (19056-80-5) → ethanol (64-17-5) + ethyl 7,8-dichloro-4-hydroxyquinoline-3-carboxylate (75001-53-5)

Guidance literature:

In diphenylether; at 250 ℃; for 1.5h;

Reference yield:

2,3-Dichlor-anilinomethylen-malonsaeure-diethylester (19056-80-5) → 7,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester (175134-95-9,75001-53-5)

Guidance literature:

With diphenyl ether-biphenyl eutectic; at 250 ℃; for 1h; Yield given;

DOI:10.1002/(SICI)1097-458X(199611)34:11<972::AID-OMR994>3.0.CO;2-9

Reference yield:

2,3-dichloroaniline (608-27-5) → 7,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester (175134-95-9,75001-53-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / Heating

2: various solvent(s) / 1 h / Heating

In various solvent(s);

DOI:10.1021/jm050048t

upstream raw materials:

2,3-Dichlor-anilinomethylen-malonsaeure-diethylester

2,3-dichloroaniline

diethyl 2-ethoxymethylenemalonate

Downstream raw materials:

7,8-dichloro-4-quinolinol-3-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 75001-53-5 7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send