2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate)

Base Information

• Chemical Name: 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate)
• CAS No.: 114828-09-0
• Molecular Formula: C₅₁H₄₈O₁₂P₂
• Molecular Weight: 914.882
• Mol file: 114828-09-0.mol

Synonyms:2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate)

Chemical Property of 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate)

There total 8 articles about 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,4,6-tri-O-benzyl-myo-inositol (114828-08-9) + chlorophosphoric acid diphenyl ester (2524-64-3) → 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate) (114828-09-0) + 1-O-diphenylphosphate-2,4,6-tri-O-benzyl-D-myo-inositol (376590-85-1)

Guidance literature:

With L-His-L-Asn-L-His-D-(L-Ala)Asp-deriv. catalyst; triethylamine; In toluene; at 0 ℃; for 8h;

DOI:10.1021/ja016779+

Reference yield: 38.0%

2,4,6-tri-O-benzyl-myo-inositol (114828-08-9) + chlorophosphoric acid diphenyl ester (2524-64-3) → 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate) (114828-09-0) + 2,4,6-tri-O-benzyl-myo-inositol 1,5-bis(diphenylphosphate) (114828-09-0,125356-32-3)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 25 ℃; for 5h; Yields of byproduct given;

Reference yield: 38.0%

2,4,6-tri-O-benzyl-myo-inositol (114828-08-9) + chlorophosphoric acid diphenyl ester (2524-64-3) → 2,4,6-tri-O-benzyl-myo-inositol 1,3-bis(diphenylphosphate) (114828-09-0) + 2,4,6-tri-O-benzyl-myo-inositol 1,5-bis(diphenylphosphate) (114828-09-0,125356-32-3)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 25 ℃; for 5h; Yields of byproduct given;

upstream raw materials:

2,4,6-tri-O-benzyl-myo-inositol

chlorophosphoric acid diphenyl ester

benzyl bromide

myo-Inositol orthoformate

Downstream raw materials:

Inositol 1,3-bisphosphate