2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid

Base Information

• Chemical Name: 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid
• CAS No.: 1610596-69-4
• Molecular Formula: C₂₁H₃₁N₅O₇
• Molecular Weight: 465.506
• Mol file: 1610596-69-4.mol

Synonyms:2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid

Chemical Property of 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid

There total 3 articles about 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2',2-(2-((2-(4-nitrophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid (1610596-68-3) → 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid (1610596-69-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In water;

Reference yield:

2,2',2-(2-(aminomethyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid (1610596-67-2) → 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid (1610596-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 2 h / pH 9.4

2: hydrogen; palladium 10% on activated carbon / water

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; In water; acetonitrile;

Reference yield:

4-nitrophenylacetic acid O-(N-hydroxy)succinimide ester (68123-33-1) → 2,2',2-(2-((2-(4-aminophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid (1610596-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 2 h / pH 9.4

2: hydrogen; palladium 10% on activated carbon / water

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; In water; acetonitrile;

upstream raw materials:

2,2',2-(2-((2-(4-nitrophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid

2,2',2-(2-(aminomethyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid

4-nitrophenylacetic acid O-(N-hydroxy)succinimide ester

Downstream raw materials:

2,2',2-(2-((2-(4-isothiocyanatophenyl)acetamido)methyl)-1,4,7-triazacyclononane-1,4,7-triyl)triacetic acid