4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl

Base Information

• Chemical Name: 4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl
• CAS No.: 1422058-64-7
• Molecular Formula: C₁₅H₂₀BrN₂O₂
• Molecular Weight: 340.24
• Mol file: 1422058-64-7.mol

Synonyms:4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl

Chemical Property of 4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl

There total 1 articles about 4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

aniline (62-53-3) + 4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid (78033-69-9) → 4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl (1422058-64-7)

Guidance literature:

4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid; With pyridine; thionyl chloride; In benzene; at 0 - 20 ℃;

aniline; With triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1055/s-0032-1317516

Reference yield: 38.0%

4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl (1422058-64-7) → 4-bromo-2,2,5,5-tetramethyl-N-phenyl-2,5-dihydro-1H-pyrrole-3-carboxamide (1422058-66-9)

Guidance literature:

4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl; With iron; acetic acid; at 70 ℃; for 0.5h;

With potassium carbonate; In water; pH=10;

DOI:10.1055/s-0032-1317516

Reference yield: 22.0%

4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl (1422058-64-7) → 4,4′-diselenobis{2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl} (1422058-65-8)

Guidance literature:

With selenium; copper(l) iodide; 1,10-Phenanthroline; potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 26h; Inert atmosphere; Sealed tube;

DOI:10.1055/s-0032-1317516

upstream raw materials:

aniline

4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid

Downstream raw materials:

4-bromo-2,2,5,5-tetramethyl-N-phenyl-2,5-dihydro-1H-pyrrole-3-carboxamide

4,4,6,6-tetramethyl-2-phenyl-5,6-dihydro-2H-pyrrolo[3,4-d][1,2]selenazol-3(4H)-one

4,4′-diselenobis{2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl}