78033-69-9

Basic information

• Product Name: 4-Bromo-1-oxyl-2,2,5,5-tetramethyl-δ3-pyrroline-3-carboxylic Acid
• Synonyms: 4-Bromo-1-oxyl-2,2,5,5-tetramethyl-δ3-pyrroline-3-carboxylic Acid;3-BroMo-4-carboxy-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy
• CAS NO: 78033-69-9
• Molecular Formula: C₉H₁₃BrNO₃
• Molecular Weight: 264.11636
• Product Categories: Spin Labeling Compounds
• Mol File: 78033-69-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: >220?C(dec.)
• Boiling Point: 349.678°C at 760 mmHg
• Flash Point: 165.28°C
• Appearance: /
• Density: 1.558g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
• CAS DataBase Reference: 4-Bromo-1-oxyl-2,2,5,5-tetramethyl-δ3-pyrroline-3-carboxylic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-1-oxyl-2,2,5,5-tetramethyl-δ3-pyrroline-3-carboxylic Acid(78033-69-9)
• EPA Substance Registry System: 4-Bromo-1-oxyl-2,2,5,5-tetramethyl-δ3-pyrroline-3-carboxylic Acid(78033-69-9)

Safety Data

• Hazardous Substances Data: 78033-69-9(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

InChI:InChI=1/C9H14BrNO3/c1-8(2)5(7(12)13)6(10)9(3,4)11(8)14/h14H,1-4H3,(H,12,13)

Upstream product

• 45985-26-0 4-oxo-2,2,6,6-tetramethylpiperidin-oxyl 
• 85591-99-7 3-bromo-4-formyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl radical 
• 85466-58-6 1-oxyl-3-bromo-2,2,5,5-tetramethyl-Δ³-pyrrolin-4-carboxylic acid and methoxycarbonic acid mixed anhydride 
• 85591-93-1 3-bromo-4-hydroxymethyl-2,2,5,5-tetramethyl-Δ³-pyrrolin-1-oxyl 
• 85065-49-2 1-oxyl-3-bromo-2,2,5,5-tetramethyl-Δ³-pyrrolin-4-carboxylic acid chloride 

Downstream Products

• 1422058-66-9 4-bromo-2,2,5,5-tetramethyl-N-phenyl-2,5-dihydro-1H-pyrrole-3-carboxamide 
• 1422058-67-0 4,4,6,6-tetramethyl-2-phenyl-5,6-dihydro-2H-pyrrolo[3,4-d][1,2]selenazol-3(4H)-one 
• 1422058-65-8 4,4′-diselenobis{2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl} 
• 1422058-64-7 4-bromo-2,2,5,5-tetramethyl-3-[(phenylamino)carbonyl]-2,5-dihydro-1H-pyrrol-1-oxyl 
• 85591-93-1 3-bromo-4-hydroxymethyl-2,2,5,5-tetramethyl-Δ³-pyrrolin-1-oxyl 
• 85591-99-7 3-bromo-4-formyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl radical 

Relevant articles and documents

A Bifunctional Spin Label for Ligand Recognition on Surfaces

In situ monitoring of biomolecular recognition, especially at surfaces, still presents a significant technical challenge. Electron paramagnetic resonance (EPR) of biomolecules spin-labeled with nitroxides can offer uniquely sensitive and selective insights into these processes, but new spin-labeling strategies are needed. The synthesis and study of a bromoacrylaldehyde spin label (BASL), which features two attachment points with orthogonal reactivity is reported. The first examples of mannose and biotin ligands coupled to aqueous carboxy-functionalized gold nanoparticles through a spin label are presented. EPR spectra were obtained for the spin-labeled ligands both free in solution and attached to nanoparticles. The labels were recognized by the mannose-binding lectin, Con A, and the biotin-binding protein avidin-peroxidase. Binding gave quantifiable changes in the EPR spectra from which binding profiles could be obtained that reflect the strength of binding in each case.

HALOGEN-CONTAINING NITROXYL RADICALS. COMMUNICATION 2. THE REACTION OF 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINE-1-OXYL WITH SODIUM HYPOBROMITE

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