(2S)-2-{[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY}-4-METHYLPENTANOIC ACID

Base Information

Chemical Name:(2S)-2-{[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY}-4-METHYLPENTANOIC ACID
CAS No.:186193-10-2
Molecular Formula:C16H29 N O6
Molecular Weight:331.4
Hs Code.:
Mol file:186193-10-2.mol

Synonyms:Pentanoicacid, 2-[3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,2-dimethyl-1-oxopropoxy]-4-methyl-,(S)-

Suppliers and Price of (2S)-2-{[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY}-4-METHYLPENTANOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-((3-((tert-Butoxycarbonyl)amino)-2,2-dimethylpropanoyl)oxy)-4-methylpentanoicacid 97%
5g
$ 982.00

Crysdot
(S)-2-((3-((tert-Butoxycarbonyl)amino)-2,2-dimethylpropanoyl)oxy)-4-methylpentanoicacid 97%
1g
$ 327.00

Total 4 raw suppliers

Chemical Property of (2S)-2-{[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY}-4-METHYLPENTANOIC ACID

Chemical Property:

PSA：101.93000
LogP:2.97070

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-((3-((tert-Butoxycarbonyl)amino)-2,2-dimethylpropanoyl)oxy)-4-methylpentanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S)-2-{[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY}-4-METHYLPENTANOIC ACID

There total 7 articles about (2S)-2-{[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY}-4-METHYLPENTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 642087-20-5
2-(3-tert-butoxycarbonylamino-2,2-dimethyl-propionyloxy)-4-methyl-pentanoic acid benzyl ester

: 186193-10-2
(2S)-<3-<<(1-dimethylethoxy)carbonyl>amino>-2,2-dimethyl-1-oxopropoxy>-4-methylpentanoic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 23 ℃; for 1.5h;
DOI:10.1021/jo035077v

Reference yield: 95.0%

: 186193-10-2
(2S)-<3-<<(1-dimethylethoxy)carbonyl>amino>-2,2-dimethyl-1-oxopropoxy>-4-methylpentanoic acid

Guidance literature:

Reference yield:

: 37755-48-9,40298-04-2
benzyl (2S)-2-hydroxy-4-methylpentanoate

: 186193-10-2
(2S)-<3-<<(1-dimethylethoxy)carbonyl>amino>-2,2-dimethyl-1-oxopropoxy>-4-methylpentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / EDCI; DMAP / CH₂Cl₂ / 17 h / 23 °C

2: 100 percent / H₂ / Pd/C / ethyl acetate / 1.5 h / 23 °C

With dmap; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In dichloromethane; ethyl acetate;
DOI:10.1021/jo035077v