37366-09-9

Usage

Uses

Used in Chemical Synthesis:
Benzeneruthenium(II) chloride dimer is used as a catalyst for the nucleophilic aromatic substitution (SNAr) reactions of fluoroarenes and cyclic amines. It facilitates the substitution of fluorine atoms in these compounds with nucleophiles, making it a valuable tool in the synthesis of various organic molecules.
Used in Hydrogenation Processes:
In the pharmaceutical and fine chemicals industries, Benzeneruthenium(II) chloride dimer is used as a precatalyst for the hydrogenation of β-keto esters. This process involves the reduction of the carbonyl group in β-keto esters to form the corresponding alcohol, which is a crucial step in the synthesis of numerous pharmaceuticals and specialty chemicals.
Used in Catalyst Preparation:
Benzeneruthenium(II) chloride dimer also serves as a precursor for the preparation of other ruthenium catalysts. These catalysts find applications in various industrial processes, including the production of polymers, pharmaceuticals, and fine chemicals, as well as in the development of new synthetic methodologies.
Overall, Benzeneruthenium(II) chloride dimer is a versatile and valuable compound in the field of chemistry, playing a significant role in the synthesis of various organic molecules and the development of new catalytic processes.

InChI:InChI=1/2C6H6.4ClH.2Ru/c2*1-2-4-6-5-3-1;;;;;;/h2*1-6H;4*1H;;/q;;;;;;2*+2/p-4

Upstream product

• 143-66-8 sodium tetraphenyl borate 
• 68193-73-7 tri-μ-methoxybis[(η-benzene)ruthenium(II)] tetraphenylborate 
• 14898-67-0 ruthenium trichloride trihydrate 
• 64-17-5 ethanol 
• 2886-59-1 1-methoxycyclohexa-1,4-diene 

Downstream Products

• 130036-46-3 {(C₆H₆)RuCl(NH₂C₆H₄CH₃)2}⁽¹⁺⁾*PF₆^(1-)={(C₆H₆)RuCl(NH₂C₆H₄CH₃)2}PF₆ 
• 130036-43-0 [(η⁶-benzene)RuCl₂(4-methylaniline)] 
• 853412-10-9 (dppf)RuCl₂(enethylenediamine) 
• 936323-02-3 [(η6-C6H6)Ru(PhCH2NH2)Cl2] 
• 1287-13-4 bis(η⁵-cyclopentadienyl)ruthenium 
• 114594-63-7 (tetrabutylammonium)7Ru(C₆H₆)(P₂W₁₅Nb₃O₆₂) 

Relevant academic research and scientific papers

A convenient one-pot synthesis of a functionalized-arene ruthenium half-sandwich compound [RuCl2(η6-C6H 5OCH2CH2OH)]2

Reaction of RuCl3·xH2O with 1-methoxy-1,4-cyclohexadiene in an alcohol solvent, ROH, gives [RuCl 2-(η6-C6H5OR)]2 (R = Me, Et, or HOCH2CH2) in up to 79% yield. The crystal structures of [Ru2(μ-Cl3)(η6-C 6H5-OEt)2]+[BPh4] - and [RuCl2(η6-C6H 5OCH2CH2OH)]2 are also reported.

STRUCTURAL CHARACTERISATION OF HYDROXO-BRIDGED ARENE-RUTHENIUM AND -OSMIUM COMPLEXES: FURTHER REACTIONS OF HYDROXO-BRIDGED COMPLEXES

Reaction of 2> with an excess of either aqueous NaOH or Na2CO3 followed by addition of Na gave two products, previously formulated as BPh4 (II) and BPh4*Me2CO (M = Ru (III), Os (IV)).X-ray structural analyses now reveal that the latter should be reformulated as the novel 2-OH)4(μ4-O)>(BPh4)2*2Me2CO tetramers containing a tetrahedrally coordinated O2- ion.In contrast, with substituted arenes the binuclear triple hydroxo-bridged cations of type III are formed asevidenced by the X-ray crystal structure determination of Cl*3H2O (V).Reactions of these various hydroxo-bridged complexes with HX (X = Cl, Br, I) gives either + and/or 2> whereas with CF3CO2H in the presence of arene', the dications 2+ are formed.

SYNTHESIS AND REACTIONS OF SOME TRIPLE ALKOXO- AND THIOATO-BRIDGED ARENERUTHENIUM(II) COMPLEXES. X-RAY STRUCTURE DETERMINATION OF

Reaction of 2> (arene = C6H6, 1,4-MeC6H4CHMe2) with NaNH2 in CH3CN gives a dark oil which upon treatment with ROH/NaBPh4 (R = Me, Et) gives the triple bridged complexes (BPh4>.The structure of the benzene complex (R = Me) has been verified by X-ray analysis.The crystals are monoclinic, space group P21/n with a 11.725(4), b 15.573(5), c 18.739(2) Angstroem; β 103.29(2)deg.These complexes undergo reactions with tertiary phosphines and hydrogen halides.There is also spectroscopic evidence for intermolecular exchange of the bridging alkoxo ligands on mixing pure solutions of the + cations (M = Ru, Os).Reaction of 2> with Pb(SEt) 2 in CH3CN gives the analogous + cations.