(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Base Information

Chemical Name:(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester
CAS No.:200057-63-2
Molecular Formula:C₅₄H₆₅N₅O₉
Molecular Weight:928.138
Hs Code.:

(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Synonyms:(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Suppliers and Price of (S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

There total 6 articles about (S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2018-66-8
Z-Leu-OH

: 200057-63-2
(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / DCC, DMAP / CH₂Cl₂ / 24 h / 4 °C

2: H₂, AcOH / 5percent Pd/C / tetrahydrofuran / 5 h

3: Et₃N / dimethylformamide / 48 h / 15 °C

4: H₂, AcOH / 5percent Pd/C / tetrahydrofuran / 5 h

5: Et₃N / dimethylformamide / 24 h / 4 °C

With dmap; hydrogen; acetic acid; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.1782

Reference yield:

: 700-57-2
1-adamantanol

: 200057-63-2
(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / DCC, DMAP / CH₂Cl₂ / 24 h / 4 °C

2: H₂, AcOH / 5percent Pd/C / tetrahydrofuran / 5 h

3: Et₃N / dimethylformamide / 48 h / 15 °C

4: H₂, AcOH / 5percent Pd/C / tetrahydrofuran / 5 h

5: Et₃N / dimethylformamide / 24 h / 4 °C

With dmap; hydrogen; acetic acid; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.1782

Reference yield:

: (S)-2-Amino-4-methyl-pentanoic acid adamantan-2-yl ester

: 200057-63-2
(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid adamantan-2-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / dimethylformamide / 48 h / 15 °C

2: H₂, AcOH / 5percent Pd/C / tetrahydrofuran / 5 h

3: Et₃N / dimethylformamide / 24 h / 4 °C

With hydrogen; acetic acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.1782