(S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

Base Information

Chemical Name:(S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate
CAS No.:1372175-85-3
Molecular Formula:C₂₄H₂₅ClN₂O₄S
Molecular Weight:472.993
Hs Code.:

Synonyms:(S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

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Chemical Property of (S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

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Technology Process of (S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

There total 3 articles about (S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 178264-57-8
ethyl 6-(bromomethyl)-nicotinate

: 1372175-67-1
(S)-4-chloro-N-(1-phenylpropyl)benzenesulfonamide

: 1372175-85-3
(S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield:

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 1372175-85-3
(S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran / 6 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 3789-59-1
(R)-1-phenylpropylamine

: 1372175-85-3
(S)-ethyl 6-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)nicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran / 6 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;