2-Piperidinecarboxylicacid,4-methyl-,methylester,(2R-cis)-(9CI)

Base Information

Chemical Name:2-Piperidinecarboxylicacid,4-methyl-,methylester,(2R-cis)-(9CI)
CAS No.:184880-05-5
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
Mol file:184880-05-5.mol

Synonyms:2-Piperidinecarboxylicacid, 4-methyl-, methyl ester, (2R-cis)- (9CI)

Suppliers and Price of 2-Piperidinecarboxylicacid,4-methyl-,methylester,(2R-cis)-(9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Piperidinecarboxylicacid,4-methyl-,methylester,(2R-cis)-(9CI)

Chemical Property:

Boiling Point:205.9±33.0 °C(Predicted)
PKA:6.39±0.10(Predicted)
Density:0.982±0.06 g/cm3(Predicted)

Purity/Quality:

Safty Information:

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Technology Process of 2-Piperidinecarboxylicacid,4-methyl-,methylester,(2R-cis)-(9CI)

There total 2 articles about 2-Piperidinecarboxylicacid,4-methyl-,methylester,(2R-cis)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4-methyl-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

: 144817-80-1,184880-03-3,184880-05-5,259538-27-7,339183-93-6
methyl pipecolinate

Guidance literature:: With hydrogenchloride; In ethyl acetate;
DOI:10.1016/S0040-4039(01)00138-1

Reference yield:

: 123387-50-8
4-methylpiperidine-1-carboxylic acid tert-butyl ester

: 144817-80-1,184880-03-3,184880-05-5,259538-27-7,339183-93-6
methyl pipecolinate

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent Turnov_. / sec-BuLi; TMEDA / diethyl ether / 5 h / -90 - 20 °C

2: 100 percent / HCl / ethyl acetate

With hydrogenchloride; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In diethyl ether; ethyl acetate;
DOI:10.1016/S0040-4039(01)00138-1