Dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate

Base Information

Chemical Name:Dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate
CAS No.:65974-52-9
Molecular Formula:C12H11 N O6
Molecular Weight:265.222
Hs Code.:
NSC Number:126224
DSSTox Substance ID:DTXSID00298788
ChEMBL ID:CHEMBL1569494

Synonyms:dimethyl 2-(2-nitrobenzylidene)malonate;NCI126224

Suppliers and Price of Dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate

Chemical Property:

Vapor Pressure:2.03E-05mmHg at 25°C
Boiling Point:361.7°Cat760mmHg
Flash Point:151.8°C
Density:1.335g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:265.05863707
Heavy Atom Count:19
Complexity:380

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C(=CC1=CC=CC=C1[N+](=O)[O-])C(=O)OC

Technology Process of Dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate

There total 2 articles about Dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 552-89-6
2-nitro-benzaldehyde

: 108-59-8
malonic acid dimethyl ester

: 65974-52-9
dimethyl 2-[(2-nitrophenyl)methylidene]malonate

Guidance literature:: With piperidine; acetic acid; In benzene; at 80 ℃; for 15h; Microwave irradiation;
DOI:10.1021/jm401902n

Reference yield:

: 110-89-4
piperidine

: 552-89-6
2-nitro-benzaldehyde

: 108-59-8
malonic acid dimethyl ester

: 65974-52-9
dimethyl 2-[(2-nitrophenyl)methylidene]malonate

Guidance literature:: With acetic acid; In methanol; water;

Reference yield: 99.0%

: 939799-25-4
(3-bromobenzylideneamino)acetic acid methyl ester

: 65974-52-9
dimethyl 2-[(2-nitrophenyl)methylidene]malonate

: trimethyl (2S,3S,5S)-5-(3-bromophenyl)-3-(2-nitrophenyl)pyrrolidine-2,4,4-tricarboxylate

Guidance literature:: With tetrakis(acetonitrile)copper(I)tetrafluoroborate; (R(P))-2-(tert-butylsulfenyl)-1-(diphenylphosphino)ferrocene; triethylamine; In dichloromethane; at 20 ℃; enantioselective reaction;
DOI:10.1016/j.tetlet.2021.153228