(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

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Chemical Name:(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester
CAS No.:171671-74-2
Molecular Formula:C₄₄H₆₁N₃O₆
Molecular Weight:727.985
Hs Code.:

Synonyms:(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

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Chemical Property of (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

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Technology Process of (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

There total 4 articles about (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 171671-74-2
(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N, diethyl phosphorocyanidate / tetrahydrofuran / Ambient temperature

2: HBr, AcOH / CH₂Cl₂ / 4 h

3: Et₃N, diethyl phosphorocyanidate / tetrahydrofuran / Ambient temperature

With diethyl cyanophosphonate; hydrogen bromide; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja981363q

Reference yield:

: dodecyl l-phenylalanine hydrochloride

: 171671-74-2
(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N, diethyl phosphorocyanidate / tetrahydrofuran / Ambient temperature

2: HBr, AcOH / CH₂Cl₂ / 4 h

3: Et₃N, diethyl phosphorocyanidate / tetrahydrofuran / Ambient temperature

With diethyl cyanophosphonate; hydrogen bromide; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja981363q

Reference yield:

: 171671-71-9
(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionic acid dodecyl ester

: 171671-74-2
(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid dodecyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: HBr, AcOH / CH₂Cl₂ / 4 h

2: Et₃N, diethyl phosphorocyanidate / tetrahydrofuran / Ambient temperature

With diethyl cyanophosphonate; hydrogen bromide; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja981363q