(2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Base Information

Chemical Name:(2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran
CAS No.:96720-63-7
Molecular Formula:C₁₉H₂₆O₃
Molecular Weight:302.414
Hs Code.:

Synonyms:(2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Suppliers and Price of (2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

There total 11 articles about (2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 96720-62-6,114340-10-2,114340-11-3
(2R,3S,6R-)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-2-(1-hydroxypropyl)-3-methyl-2H-pyran

: 96720-63-7
(2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Guidance literature:: With dichromic acid; In water; acetone; at 25 ℃; for 0.25h;
DOI:10.1016/S0040-4039(00)98423-5

Reference yield:

: 96720-56-8
(1R,2S)-<3-(benzyloxy)-2-methyl-1-(ethenyl)propoxy>acetic acid 1,1-dimethylethyl ester

: 96720-63-7
(2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) O₃; 2.) Me₂S / 1.) methylene dichloride, -78 deg C; 2.) room temp., 2 h

2: diethyl ether / 2 h / -78 °C

3: 99 percent / 1.) trifluoroacetic acid / benzene / 3 h / Heating

5: 1.) i-Bu₂AlH / 1.) diethyl ether, THF, -78 deg C, 1.5 h; 2.) THF, room temp., 2 h

6: 93 percent / H₂Cr₂O₇ / acetone; propan-2-ol; H₂O / 0.25 h / 25 °C

With dimethylsulfide; dichromic acid; diisobutylaluminium hydride; ozone; trifluoroacetic acid; In diethyl ether; water; isopropyl alcohol; acetone; benzene;
DOI:10.1016/S0040-4020(01)90568-X

Reference yield:

: 96720-54-6
(3R,4S)-5-(benzyloxy)-3-hydroxy-4-methyl-1-pentene

: 96720-63-7
(2R,3S,6R)-6-<2-(benzyloxy)-1(S)-methyl>ethyl-3,6-dihydro-3-methyl-2-(1-oxopropyl)-2H-pyran

Guidance literature:: Multi-step reaction with 8 steps

1: 97 percent / NaH / tetrahydrofuran / 12 h / Heating

2: 88 percent / DMAP, DCC / CH₂Cl₂ / 3 h / 25 °C

3: 1.) O₃; 2.) Me₂S / 1.) methylene dichloride, -78 deg C; 2.) room temp., 2 h

4: diethyl ether / 2 h / -78 °C

5: 99 percent / 1.) trifluoroacetic acid / benzene / 3 h / Heating

7: 1.) i-Bu₂AlH / 1.) diethyl ether, THF, -78 deg C, 1.5 h; 2.) THF, room temp., 2 h

8: 93 percent / H₂Cr₂O₇ / acetone; propan-2-ol; H₂O / 0.25 h / 25 °C

With dmap; dimethylsulfide; dichromic acid; sodium hydride; diisobutylaluminium hydride; ozone; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane; water; isopropyl alcohol; acetone; benzene;
DOI:10.1016/S0040-4020(01)90568-X