1-(3,5-dimethylphenyl)-6-fluoroisoquinoline

Base Information

• Chemical Name: 1-(3,5-dimethylphenyl)-6-fluoroisoquinoline
• CAS No.: 1372215-46-7
• Molecular Formula: C₁₇H₁₄FN
• Molecular Weight: 251.303
• Mol file: 1372215-46-7.mol

Synonyms:1-(3,5-dimethylphenyl)-6-fluoroisoquinoline

Chemical Property of 1-(3,5-dimethylphenyl)-6-fluoroisoquinoline

Chemical Property:

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Technology Process of 1-(3,5-dimethylphenyl)-6-fluoroisoquinoline

There total 1 articles about 1-(3,5-dimethylphenyl)-6-fluoroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-chloro-6-fluoroisoquinoline (214045-86-0) + 3,5-dimethylphenyl boronic acid (172975-69-8) → 1-(3,5-dimethylphenyl)-6-fluoroisoquinoline (1372215-46-7)

Guidance literature:

With palladium diacetate; potassium carbonate; triphenylphosphine; In 1,2-dimethoxyethane; water; at 80 ℃;

DOI:10.1039/c2jm30207a

upstream raw materials:

1-chloro-6-fluoroisoquinoline

3,5-dimethylphenyl boronic acid