N-(pyridin-3-ylmethyl)cyclopropanamine

Base Information

• Chemical Name: N-(pyridin-3-ylmethyl)cyclopropanamine
• CAS No.: 183609-18-9
• Molecular Formula: C9H12 N2
• Molecular Weight: 148.21
• Hs Code.: 2933399090
• European Community (EC) Number: 870-516-6
• DSSTox Substance ID: DTXSID00360631
• Nikkaji Number: J777.742F
• Wikidata: Q82142470
• Mol file: 183609-18-9.mol

Synonyms:N-(pyridin-3-ylmethyl)cyclopropanamine;183609-18-9;Cyclopropyl-pyridin-3-ylmethyl-amine;N-[(3-Pyridyl)methyl]cyclopropanamine;MFCD03821869;N-[(pyridin-3-yl)methyl]cyclopropanamine;3-Pyridinemethanamine,N-cyclopropyl-(9CI);N-(3-pyridinylmethyl)cyclopropanamine;SCHEMBL664734;DTXSID00360631;Cyclopropylpyridin-3-ylmethylamine;HMS1704C04;AC4955;BBL007852;STK511388;3-Pyridinemethanamine, N-cyclopropyl-;AKOS000264143;SB52576;CS-11294;SY028835;BB 0258582;CS-0208331;EN300-13854;cyclopropyl-pyridin-3-ylmethyl-amine, AldrichCPR;A880815;J-011761;Z90517827;N-(Pyridin-3-ylmethyl)cyclopropanamine

Chemical Property of N-(pyridin-3-ylmethyl)cyclopropanamine

Chemical Property:

• Vapor Pressure: 0.013mmHg at 25°C
• Melting Point: 216-217 °C(Solv: ethanol (64-17-5))
• Refractive Index: 1.559
• Boiling Point: 259.3ºC at 760 mmHg
• PKA: 7.36±0.20(Predicted)
• Flash Point: 110.6ºC
• PSA: 24.92000
• Density: 1.07g/cm3
• LogP: 1.72450
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 148.100048391
• Heavy Atom Count: 11
• Complexity: 121

Purity/Quality:

97% ^*data from raw suppliers

N-(pyridin-3-ylmethyl)cyclopropanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1NCC2=CN=CC=C2

Technology Process of N-(pyridin-3-ylmethyl)cyclopropanamine

There total 5 articles about N-(pyridin-3-ylmethyl)cyclopropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-(pyridin-3-ylmethyl)cyclopropylamine (183609-18-9) + N-Cyclopropyl-3-picolylimine (183608-99-3,502546-16-9)

Guidance literature:

Reference yield:

N-Cyclopropyl-3-picolylimine (183608-99-3,502546-16-9) → N-(pyridin-3-ylmethyl)cyclopropylamine (183609-18-9)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃;

DOI:10.1081/SCC-120024001

Reference yield:

3-pyridinecarboxaldehyde (500-22-1) + Cyclopropylamine (765-30-0) → N-(pyridin-3-ylmethyl)cyclopropylamine (183609-18-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 2.5h; under 2585.7 Torr;

DOI:10.1016/S0223-5234(97)89850-9

upstream raw materials:

3-pyridinecarboxaldehyde

Cyclopropylamine

N-Cyclopropyl-3-picolylimine

Downstream raw materials:

C₂₁H₂₀Cl₂N₄O₂