1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

Base Information

Chemical Name:1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride
CAS No.:1382037-89-9
Molecular Formula:C₁₇H₂₀N₆OS*ClH
Molecular Weight:392.912
Hs Code.:

Synonyms:1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

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Chemical Property of 1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

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Technology Process of 1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

There total 1 articles about 1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1382037-89-9
1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

Guidance literature:

Reference yield: 81.0%

: 4530-20-5
BOC-glycine

: 1382037-89-9
1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

: tert-butyl[2-({4-[3-carbamoyl-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazolin-1-yl]cyclohexyl}amino)-2-oxoethyl]carbamate

Guidance literature:: BOC-glycine; 1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride; With sodium hydrogencarbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In ISOPROPYLAMIDE; at 20 ℃; for 18h;

With sodium hydrogencarbonate; In ISOPROPYLAMIDE; water; ethyl acetate;

Reference yield: 11.0%

: 1382037-89-9
1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride

: 109-90-0
ethyl isocyanate

: 1382036-81-8
1-{4-[(ethylcarbamoyl)amino]cyclohexyl}-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

Guidance literature:: 1-(4-aminocyclohexyl)-8-(methylsulfanyl)-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide monohydrochloride; ethyl isocyanate; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 100 ℃; for 18h;

With sodium hydrogencarbonate; In water; ethyl acetate; N,N-dimethyl-formamide;