4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

Base Information

Chemical Name:4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide
CAS No.:1432508-91-2
Molecular Formula:C₁₉H₁₆FN₃O₃
Molecular Weight:353.353
Hs Code.:

Synonyms:4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

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Technology Process of 4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

There total 4 articles about 4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1432510-05-8
methyl 4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)benzoate

: 1432508-91-2
4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

Guidance literature:: With hydroxylamine; potassium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 0.5h;

Reference yield:

: 2417-72-3
Methyl 4-(bromomethyl)benzoate

: 1432508-91-2
4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / acetonitrile / 3 h / Reflux

2: potassium hydroxide; hydroxylamine / methanol; water; tetrahydrofuran / 0.5 h / 20 °C

With hydroxylamine; caesium carbonate; potassium hydroxide; In tetrahydrofuran; methanol; water; acetonitrile;

Reference yield:

: 128487-04-7
8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one

: 1432508-91-2
4-((8-fluoro-1-oxo-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)-N-hydroxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / acetonitrile / 3 h / Reflux

2: potassium hydroxide; hydroxylamine / methanol; water; tetrahydrofuran / 0.5 h / 20 °C

With hydroxylamine; caesium carbonate; potassium hydroxide; In tetrahydrofuran; methanol; water; acetonitrile;