Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate

Base Information

• Chemical Name: Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate
• CAS No.: 420847-90-1
• Molecular Formula: C₃₃H₃₃NO₄S₂
• Molecular Weight: 571.761
• Mol file: 420847-90-1.mol

Synonyms:Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate

Chemical Property of Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate

There total 1 articles about Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-BENZYLOXYCARBONYLAMINO-4-OXO-BUTYRIC ACID BENZYL ESTER (58641-56-8) + phenylmethanethiol (100-53-8) → Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate (420847-90-1)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 12h; Heating;

DOI:10.1081/SCC-120002014

Reference yield: 80.0%

Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate (420847-90-1) → Benzyl (2RS)-2-Benzyloxycarbonylamino-4-benzylthio-4-benzylsulfinylbutanoate (420847-91-2)

Guidance literature:

With sodium periodate; In 1,4-dioxane; methanol; at 20 ℃; for 20h;

DOI:10.1081/SCC-120002014

Reference yield:

Benzyl(2RS)-2-Benzyloxycarbonylamino-4,4-dibenzylthiobutanoate (420847-90-1) → Benzyl (2RS,3E)-2-Benzyloxycarbonylamino-4-benzylthio-3-butenoate

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / NaIO₄ / methanol; dioxane / 20 h / 20 °C

2: calcium carbonate / toluene / 4 h / Heating

With sodium periodate; calcium carbonate; In 1,4-dioxane; methanol; toluene;

DOI:10.1081/SCC-120002014

upstream raw materials:

2-BENZYLOXYCARBONYLAMINO-4-OXO-BUTYRIC ACID BENZYL ESTER

phenylmethanethiol

Downstream raw materials:

Benzyl (2RS)-2-Benzyloxycarbonylamino-4-benzylthio-4-benzylsulfinylbutanoate