Tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate

Base Information

Chemical Name:Tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate
CAS No.:210354-30-6
Molecular Formula:C₂₃H₃₆N₂O₆S
Molecular Weight:468.615
Hs Code.:
DSSTox Substance ID:DTXSID60696726

Synonyms:210354-30-6;tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate;DTXSID60696726;A815084;tert-Butyl S-(2-{[(benzyloxy)carbonyl]amino}ethyl)-N-(tert-butoxycarbonyl)homocysteinate;2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-4-[2-(phenylmethoxycarbonylamino)ethylthio]butanoic acid tert-butyl ester

Suppliers and Price of Tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate

Chemical Property:

Boiling Point:605.8±55.0 °C(Predicted)
Density:1.136±0.06 g/cm3(Predicted)
XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:15
Exact Mass:468.22940805
Heavy Atom Count:32
Complexity:594

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C(CCSCCNC(=O)OCC1=CC=CC=C1)NC(=O)OC(C)(C)C

Technology Process of Tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate

There total 2 articles about Tert-butyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-[2-(phenylmethoxycarbonylamino)ethylsulfanyl]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 630108-94-0
N-tert-butoxycarbonyl-L-homocysteine tert-butyl ester

: 210354-30-6
4-(2-benzyloxycarbonylamino-ethylsulfanyl)-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; at 45 ℃;
DOI:10.1016/S0960-894X(00)00055-X

Reference yield:

: 601491-40-1
N,N′-di(tert-butoxycarbonyl)-L-homocystine di(tert-butyl)ester

: 210354-30-6
4-(2-benzyloxycarbonylamino-ethylsulfanyl)-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / DTT; Et₃N / CHCl₃

2: 65 percent / DBU / toluene / 45 °C

With DL-dithiothreitol; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In chloroform; toluene; 1: Reduction / 2: Condensation;
DOI:10.1016/S0960-894X(00)00055-X

Reference yield:

: 210354-30-6
4-(2-benzyloxycarbonylamino-ethylsulfanyl)-2-tert-butoxycarbonylamino-butyric acid tert-butyl ester

: 210354-22-6
GW274150

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / HCO₂NH₄ / Pd(OH)2/C / ethanol / Heating

2: ethanol

3: HCl / dioxane

With hydrogenchloride; ammonium formate; palladium dihydroxide; In 1,4-dioxane; ethanol; 1: Hydrogenolysis / 2: Condensation / 3: Hydrolysis; Decarboxylation;
DOI:10.1016/S0960-894X(00)00055-X