6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Base Information

Chemical Name:6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid
CAS No.:765300-80-9
Molecular Formula:C₄₀H₆₀O₅Si₂
Molecular Weight:677.084
Hs Code.:

6-benzyloxy-3-(<i>tert</i>-butyl-dimethyl-silanyloxy)-8-(<i>tert</i>-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Synonyms:6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Suppliers and Price of 6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

There total 13 articles about 6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 765300-79-6
6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanal

: 765300-80-9
6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In tert-butyl alcohol; at 20 ℃; for 3h;
DOI:10.1016/j.tetasy.2004.06.023

Reference yield:

: 100-39-0
benzyl bromide

: 765300-80-9
6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Guidance literature:: Multi-step reaction with 12 steps

1.1: 83 percent / NaH / tetrahydrofuran / 6 h / 20 °C

2.1: 85 percent / CSA / methanol; H₂O / 12 h / 20 °C

3.1: 66 percent / Et₃N / CH₂Cl₂ / 16 h / 20 °C

4.1: 88 percent / K₂CO₃ / methanol / 1 h / 20 °C

5.1: 93 percent / n-BuLi / toluene / 12 h / -20 - 20 °C

6.1: 92 percent / imidazole / CH₂Cl₂ / 4 h / 20 °C

7.1: 56 percent / BH₃*Me₂S; aq. NaOH; H₂O₂ / tetrahydrofuran; methanol / 12 h / 20 °C

8.1: 98 percent / IBX / dimethylsulfoxide / 6 h / 20 °C

9.1: TiCl₄; TMEDA / CH₂Cl₂ / 0.5 h / 0 °C

9.2: 54 percent / CH₂Cl₂ / 0.5 h / -78 °C

10.1: 80 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 20 °C

11.1: 83 percent / DIBAL-H / CH₂Cl₂ / 0.25 h / -78 °C

12.1: 92 percent / NaClO₂; NaH₂PO₄; 2-methyl-2-butene / 2-methyl-propan-2-ol / 3 h / 20 °C

With 1H-imidazole; 2,6-dimethylpyridine; sodium hydroxide; sodium chlorite; sodium dihydrogenphosphate; n-butyllithium; 2-methyl-but-2-ene; N,N,N,N,-tetramethylethylenediamine; dimethylsulfide borane complex; camphor-10-sulfonic acid; dihydrogen peroxide; titanium tetrachloride; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triethylamine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; toluene; tert-butyl alcohol;
DOI:10.1016/j.tetasy.2004.06.023

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 765300-80-9
6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-2-methyl-decanoic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: 92 percent / imidazole / CH₂Cl₂ / 4 h / 20 °C

2.1: 56 percent / BH₃*Me₂S; aq. NaOH; H₂O₂ / tetrahydrofuran; methanol / 12 h / 20 °C

3.1: 98 percent / IBX / dimethylsulfoxide / 6 h / 20 °C

4.1: TiCl₄; TMEDA / CH₂Cl₂ / 0.5 h / 0 °C

4.2: 54 percent / CH₂Cl₂ / 0.5 h / -78 °C

5.1: 80 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 20 °C

6.1: 83 percent / DIBAL-H / CH₂Cl₂ / 0.25 h / -78 °C

7.1: 92 percent / NaClO₂; NaH₂PO₄; 2-methyl-2-butene / 2-methyl-propan-2-ol / 3 h / 20 °C

With 1H-imidazole; 2,6-dimethylpyridine; sodium hydroxide; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; N,N,N,N,-tetramethylethylenediamine; dimethylsulfide borane complex; dihydrogen peroxide; titanium tetrachloride; diisobutylaluminium hydride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; tert-butyl alcohol;
DOI:10.1016/j.tetasy.2004.06.023