(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate

Base Information

• Chemical Name: (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate
• CAS No.: 1245942-37-3
• Molecular Formula: C₂₉H₃₀N₂O₅
• Molecular Weight: 486.568
• Mol file: 1245942-37-3.mol

Synonyms:(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate

Chemical Property of (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate

There total 1 articles about (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

benzoic acid (65-85-0,8013-63-6) + (S)-5-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-methoxy-6-oxohexan-1-aminium chloride (847658-45-1) → (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate (1245942-37-3)

Guidance literature:

With pyridine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 0 - 20 ℃; Molecular sieve;

DOI:10.1016/j.bmc.2010.06.035

Reference yield: 50.0%

(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate (1245942-37-3) → (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoic acid (1007096-37-8)

Guidance literature:

(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoate; With water; calcium chloride; sodium hydroxide; In isopropyl alcohol; at 20 ℃; for 5h;

With acetic acid; In water; isopropyl alcohol;

DOI:10.1016/j.bmc.2010.06.035

upstream raw materials:

benzoic acid

(S)-5-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-methoxy-6-oxohexan-1-aminium chloride

Downstream raw materials:

(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-benzamidohexanoic acid