C₂₄H₃₁NO₄

Base Information

• Chemical Name: C₂₄H₃₁NO₄
• CAS No.: 1402451-01-7
• Molecular Formula: C₂₄H₃₁NO₄
• Molecular Weight: 397.514
• Mol file: 1402451-01-7.mol

Synonyms:C₂₄H₃₁NO₄

Chemical Property of C₂₄H₃₁NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₁NO₄

There total 1 articles about C₂₄H₃₁NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C17H25NO4 (1402451-00-6) + benzyl bromide (100-39-0) → C24H31NO4 (1402451-01-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/chem.201201415

Reference yield:

C24H31NO4 (1402451-01-7) → C76H104N8O11 (1402450-99-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere

3.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

4.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

4.2: 20 °C / Inert atmosphere

5.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

6.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

6.2: 120 h / 20 °C / Inert atmosphere

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.201201415

Reference yield:

C24H31NO4 (1402451-01-7) → C25H39N3O6 (1402451-07-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere

3.1: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / Inert atmosphere

4.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

4.2: 72 h / 20 °C / Inert atmosphere

5.1: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.201201415

upstream raw materials:

C₁₇H₂₅NO₄

benzyl bromide

Downstream raw materials:

C₂₅H₃₉N₃O₆

C₃₂H₄₆N₄O₅

C₂HF₃O₂*C₃₅H₄₅N₃O₄

C₇₆H₁₀₄N₈O₁₁