2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole

Base Information

• Chemical Name: 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole
• CAS No.: 219558-95-9
• Molecular Formula: C₂₇H₃₂N₂O₆
• Molecular Weight: 480.561

Synonyms:2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole

Chemical Property of 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole

There total 7 articles about 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2--3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-Nb-benzylamino>ethyl>indole (219558-86-8) → 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-Nb-benzylamino>ethyl>indole (219558-95-9)

Guidance literature:

With water; lithium chloride; In N,N-dimethyl-formamide; at 135 ℃; for 4h;

DOI:10.1021/jo9813989

Reference yield:

benzaldehyde (100-52-7) → 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-Nb-benzylamino>ethyl>indole (219558-95-9)

Guidance literature:

Multi-step reaction with 5 steps

1: MgSO₄ / CH₂Cl₂ / 5 h

2: NaBH₄ / methanol / 1 h / 0 °C

3: 28.5 g / Et₃N / CH₂Cl₂ / Ambient temperature

5: 33.1 g / LiCl, H₂O / dimethylformamide / 4 h / 135 °C

With sodium tetrahydroborate; water; magnesium sulfate; triethylamine; lithium chloride; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo9813989

Reference yield:

(S)-tryptophan methyl ester hydrochloride (7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8) → 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-Nb-benzylamino>ethyl>indole (219558-95-9)

Guidance literature:

Multi-step reaction with 4 steps

2: 28.5 g / Et₃N / CH₂Cl₂ / Ambient temperature

4: 33.1 g / LiCl, H₂O / dimethylformamide / 4 h / 135 °C

With water; triethylamine; lithium chloride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo9813989

upstream raw materials:

2--3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole

(S)-tryptophan methyl ester hydrochloride

methyl N-benzyl-L-tryptophanate

N_b-benzylidene-L-tryptophan methyl ester

Downstream raw materials:

2-<(methoxycarbonyl)methyl>-3-<2-(S)-(methoxycarbonyl)-2-(N^b-benzylamino)ethyl>indole

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-5-formyl-1H-pyrrolo<2,3-d>carbazole-6-carboxylate

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-5-(1-propenyl)-1H-pyrrolo<2,3-d>carbazole-6-carboxylate

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-5-(dimethoxymethyl)-1H-pyrrolo<2,3-d>carbazole-6-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 219558-95-9 2-<(methoxycarbonyl)methyl>-3-<2(S)-(methoxycarbonyl)-2-b-(tert-butoxycarbonyl)-N^b-benzylamino>ethyl>indole

Send

Send

Metric Ton KG G Pound L ML

Send

Send