1-Benzylpiperidine-3-carbohydrazide

Base Information

Chemical Name:1-Benzylpiperidine-3-carbohydrazide
CAS No.:182919-58-0
Molecular Formula:C13H19 N3 O
Molecular Weight:233.313
Hs Code.:2933399090
DSSTox Substance ID:DTXSID10385774
Nikkaji Number:J1.553.882A
Mol file:182919-58-0.mol

Synonyms:1-benzylpiperidine-3-carbohydrazide;182919-58-0;SCHEMBL4792478;DTXSID10385774;AKOS005289484;CS-0258569;FT-0749527;A25586;EN300-7054372

Suppliers and Price of 1-Benzylpiperidine-3-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Benzylpiperidine-3-carbohydrazide 95+%
1g
$ 429.00

Chemenu
1-benzylpiperidine-3-carbohydrazide 95%
1g
$ 405.00

American Custom Chemicals Corporation
1-(PHENYLMETHYL)-3-PIPERIDINECARBOXYLIC HYDRAZIDE 95.00%
5MG
$ 505.58

Alichem
1-Benzylpiperidine-3-carbohydrazide
1g
$ 381.50

Total 8 raw suppliers

Chemical Property of 1-Benzylpiperidine-3-carbohydrazide

Chemical Property:

Boiling Point:415.3±34.0 °C(Predicted)
PKA:13.23±0.20(Predicted)
PSA：61.85000
Density:1.149±0.06 g/cm3(Predicted)
LogP:2.36700
Storage Temp.:2-8°C
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.152812238
Heavy Atom Count:17
Complexity:251

Purity/Quality:

97% ^*data from raw suppliers

1-Benzylpiperidine-3-carbohydrazide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CN(C1)CC2=CC=CC=C2)C(=O)NN

Technology Process of 1-Benzylpiperidine-3-carbohydrazide

There total 4 articles about 1-Benzylpiperidine-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 72551-53-2
ethyl 1-benzylpiperidine-3-carboxylate

: 182919-58-0
(±)-1-benzylpiperidine-3-carbohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; Reflux;
DOI:10.1016/j.ejmech.2016.11.006

Reference yield:

: 100-39-0
benzyl bromide

: 182919-58-0
(±)-1-benzylpiperidine-3-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / Na₂CO₃ / CH₂Cl₂; H₂O / 3 h / Heating

2: 95 percent / NH₂NH₂*H₂O / methanol / 4 h / Heating

With sodium carbonate; hydrazine hydrate; In methanol; dichloromethane; water;
DOI:10.1016/S0040-4039(01)00985-6

Reference yield:

: 100-44-7
benzyl chloride

: 182919-58-0
(±)-1-benzylpiperidine-3-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / acetonitrile / Inert atmosphere; Cooling with ice

1.2: 20 °C / Inert atmosphere

2.1: hydrazine hydrate / ethanol / Reflux

With hydrazine hydrate; triethylamine; In ethanol; acetonitrile;
DOI:10.1016/j.bioorg.2018.11.051