2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide

Base Information

• Chemical Name: 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide
• CAS No.: 83473-22-7
• Molecular Formula: C₁₅H₂₃N₃O₃
• Molecular Weight: 293.366
• Mol file: 83473-22-7.mol

Synonyms:2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide

Chemical Property of 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide

There total 3 articles about 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N,N-dimethylammonium chloride (506-59-2) + 2-Bromo-hexanoic acid (2-methyl-4-nitro-phenyl)-amide (83473-13-6) → 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide (83473-22-7)

Guidance literature:

With sodium hydrogencarbonate; In benzene; for 30h; Heating;

DOI:10.1002/jps.2600710619

Reference yield:

2-bromohexanoic acid (616-05-7) → 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide (83473-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / PCl₃ / benzene / 3 h / Heating

2: 82 percent / NaHCO₃ / benzene / 30 h / Heating

With sodium hydrogencarbonate; phosphorus trichloride; In benzene;

DOI:10.1002/jps.2600710619

Reference yield:

2-methyl-4-nitro-benzenamine (99-52-5) → 2-Dimethylamino-hexanoic acid (2-methyl-4-nitro-phenyl)-amide (83473-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / PCl₃ / benzene / 3 h / Heating

2: 82 percent / NaHCO₃ / benzene / 30 h / Heating

With sodium hydrogencarbonate; phosphorus trichloride; In benzene;

DOI:10.1002/jps.2600710619

upstream raw materials:

N,N-dimethylammonium chloride

2-Bromo-hexanoic acid (2-methyl-4-nitro-phenyl)-amide

2-bromohexanoic acid

2-methyl-4-nitro-benzenamine

Downstream raw materials:

2-Dimethylamino-hexanoic acid {4-[butyl-(toluene-4-sulfonyl)-amino]-2-methyl-phenyl}-amide

2-Dimethylamino-hexanoic acid [2-methyl-4-(toluene-4-sulfonylamino)-phenyl]-amide

2-Dimethylamino-hexanoic acid (4-amino-2-methyl-phenyl)-amide