(4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane

Base Information

• Chemical Name: (4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane
• CAS No.: 464184-41-6
• Molecular Formula: C₂₂H₂₂O₂
• Molecular Weight: 318.415
• Mol file: 464184-41-6.mol

Synonyms:(4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane

Chemical Property of (4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane

There total 1 articles about (4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexa-2,5-dienylethanal diethylacetal (53267-67-7) + (R,R)-hydroxybenzoin (52340-78-0) → (4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane (464184-41-6)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 70 ℃; for 2h;

DOI:10.1002/chem.200700871

Reference yield: 43.0%

(4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane (464184-41-6) → (4R,5R)-2-benzyl-4,5-diphenyl-1,3-dioxolane

Guidance literature:

With iodonium(di-γ-collidine) perchlorate; In dichloromethane; 2-methoxy-ethanol;

DOI:10.1248/cpb.53.952

Reference yield:

phenethylmagnesium bromide (3277-89-2) + (4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane (464184-41-6) → (1R,3R,4R,6S,8R,12R)-12-bromo-2,5-dioxa-3,4-diphenyl-6-(2-phenylethyl)bicyclo[6.4.0]-dodec-9-ene

Guidance literature:

(4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane; With N-Bromosuccinimide; 2-methoxy-ethanol; In acetonitrile; at 0 ℃; for 4h;

phenethylmagnesium bromide; In toluene; at 20 ℃; for 12h;

DOI:10.1248/cpb.53.952

upstream raw materials:

cyclohexa-2,5-dienylethanal diethylacetal

(R,R)-hydroxybenzoin

Downstream raw materials:

(1S,2R,3S,6S)-2-(2,2-Dimethoxy-ethyl)-7-oxa-bicyclo[4.1.0]heptane-2,3-diol

(1S,3R,4R,6R,8R)-6-methoxy-3,4-diphenyl-2,5-dioxabicyclo[6.4.0]dodec-9-ene

(1S,3R,5R,6R,8S)-3-methoxy-5,6-diphenyl-4,7-dioxabicyclo[6.4.0]dodec-11-en-1-ol

(1S,6S)-1-(2,2-dimethoxyethyl)-6-[(1R,2R)-2-hydroxyethoxy-1,2-diphenyl]cyclohex-2-en-1-ol