cyclohexa-2,5-dienylethanal diethylacetal

Base Information

• Chemical Name: cyclohexa-2,5-dienylethanal diethylacetal
• CAS No.: 53267-67-7
• Molecular Formula: C₁₂H₂₀O₂
• Molecular Weight: 196.29
• Mol file: 53267-67-7.mol

Synonyms:cyclohexa-2,5-dienylethanal diethylacetal

Chemical Property of cyclohexa-2,5-dienylethanal diethylacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexa-2,5-dienylethanal diethylacetal

There total 3 articles about cyclohexa-2,5-dienylethanal diethylacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

cyclohexa-1,4-diene (1165952-92-0) + Bromoacetaldehyde diethyl acetal (2032-35-1) → cyclohexa-2,5-dienylethanal diethylacetal (53267-67-7)

Guidance literature:

cyclohexa-1,4-diene; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

Bromoacetaldehyde diethyl acetal; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Further stages.;

DOI:10.1021/ol702530b

Reference yield:

cyclohexa-2,5-dienyl-methanol (25372-69-4) → cyclohexa-2,5-dienylethanal diethylacetal (53267-67-7)

Guidance literature:

Multi-step reaction with 2 steps

1: CCl₄, Ph₃P / Heating

2: (i) Mg, THF, (ii) /BRN= 1872634/

With tetrachloromethane; triphenylphosphine;

Reference yield:

diethyl phenyl orthoformate (14444-77-0) + 2,5-Cyclohexadien-1-ylmethylchlorid (53267-64-4) → cyclohexa-2,5-dienylethanal diethylacetal (53267-67-7)

Guidance literature:

Multistep reaction; (i) Mg, THF, (ii) /BRN= 1872634/;

upstream raw materials:

diethyl phenyl orthoformate

2,5-Cyclohexadien-1-ylmethylchlorid

cyclohexa-2,5-dienyl-methanol

cyclohexa-1,4-diene

Downstream raw materials:

2-(cyclohexa-2,5-dien-1-yl)acetaldehyde

(4R,5R)-2-(2,5-cyclohexadienylmethyl)-4,5-diphenyl-1,3-dioxolane

(1S,2R,3S,6S)-2-(2,2-Dimethoxy-ethyl)-7-oxa-bicyclo[4.1.0]heptane-2,3-diol

(1S,3R,4R,6R,8R)-6-methoxy-3,4-diphenyl-2,5-dioxabicyclo[6.4.0]dodec-9-ene