Technology Process of 2-(di-p-tolylphosphino)phenol
There total 4 articles about 2-(di-p-tolylphosphino)phenol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(2-hydroxyphenyl)di-p-tolylphosphane oxide;
With
trichlorosilane; N,N-dimethyl-aniline;
In
toluene;
at 20 - 80 ℃;
for 16h;
With
sodium hydroxide;
In
water; toluene;
at 0 - 50 ℃;
for 0.5h;
DOI:10.1021/ol2013236
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid / methanol / 20 °C
2.1: trichlorosilane; N,N-dimethyl-aniline / toluene / 16 h / 20 - 80 °C
2.2: 0.5 h / 0 - 50 °C
With
trichlorosilane; toluene-4-sulfonic acid; N,N-dimethyl-aniline;
In
methanol; toluene;
DOI:10.1021/ol2013236
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane / dimethyl sulfoxide / 12 h / 20 - 100 °C
2.1: toluene-4-sulfonic acid / methanol / 20 °C
3.1: trichlorosilane; N,N-dimethyl-aniline / toluene / 16 h / 20 - 80 °C
3.2: 0.5 h / 0 - 50 °C
With
trichlorosilane; palladium diacetate; toluene-4-sulfonic acid; N,N-dimethyl-aniline; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane;
In
methanol; dimethyl sulfoxide; toluene;
DOI:10.1021/ol2013236
