Technology Process of (R)-4-methyl-2-phenyl-2,5-dihydrofuran
There total 10 articles about (R)-4-methyl-2-phenyl-2,5-dihydrofuran which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
silver nitrate;
In
silica; pentane;
at 20 ℃;
for 4h;
Darkness;
DOI:10.1039/b912128p
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
diethyl ether;
at 20 ℃;
for 1h;
DOI:10.1002/anie.201103227
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: tetrakis(triphenylphosphine) palladium(0); zinc dibromide / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: sulfuric acid / methanol / 0.5 h / 0 °C
3.1: porcine pancrease lipase / 1,4-dioxane / 24 h / 40 °C / Enzymatic reaction
4.1: silver nitrate / water; acetone / 18 h / 40 °C
5.1: water; sodium hydroxide / methanol / 0.25 h / 0 °C
6.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 2 h / 0 °C
7.1: lithium aluminium tetrahydride / diethyl ether / 1 h / 20 °C
With
lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium(0); carbon tetrabromide; porcine pancrease lipase; sulfuric acid; water; silver nitrate; triphenylphosphine; sodium hydroxide; zinc dibromide;
In
tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; acetone;
DOI:10.1002/anie.201103227
