Furo[3,2-b]pyridine 4-oxide

Base Information

Chemical Name:Furo[3,2-b]pyridine 4-oxide
CAS No.:181526-18-1
Molecular Formula:C₇H₅NO₂
Molecular Weight:135.122
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70442635
Nikkaji Number:J848.371J
Wikidata:Q82260020
Mol file:181526-18-1.mol

Synonyms:furo[3,2-b]pyridine 4-oxide;181526-18-1;4-oxidofuro[3,2-b]pyridin-4-ium;furo[3,2-b]pyridine,4-oxide(9ci);Furo[3,2-b]pyridine4-oxide;SCHEMBL2796870;DTXSID70442635;IDCIIFQWJWAWTJ-UHFFFAOYSA-N;AKOS015855797;A4025;FT-0682277

Suppliers and Price of Furo[3,2-b]pyridine 4-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
FURO[3,2-B]PYRIDINE 4-OXIDE 95.00%
25G
$ 1178.79

AccelPharmtech
Furo[3,2-b]pyridine4-oxide 97.00%
2G
$ 1070.00

AccelPharmtech
Furo[3,2-b]pyridine4-oxide 97.00%
1G
$ 640.00

AccelPharmtech
Furo[3,2-b]pyridine4-oxide 97.00%
500MG
$ 460.00

Total 11 raw suppliers

Chemical Property of Furo[3,2-b]pyridine 4-oxide

Chemical Property:

Vapor Pressure:0.033mmHg at 25°C
Refractive Index:1.617
Boiling Point:251.338°C at 760 mmHg
Flash Point:105.806°C
PSA：38.60000
Density:1.317g/cm³
LogP:1.86130
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:135.032028402
Heavy Atom Count:10
Complexity:129

Purity/Quality:

97% ^*data from raw suppliers

FURO[3,2-B]PYRIDINE 4-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CO2)[N+](=C1)[O-]

Technology Process of Furo[3,2-b]pyridine 4-oxide

There total 3 articles about Furo[3,2-b]pyridine 4-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 272-62-8
furo[3,2-b]pyridine

: 181526-18-1
4-oxidofuro[3,2-b]pyridin-4-ium

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 20h; Ambient temperature;
DOI:10.1002/jhet.5570330409

Reference yield:

: 6602-32-0
2-bromo-pyridin-3-ol

: 181526-18-1
4-oxidofuro[3,2-b]pyridin-4-ium

Guidance literature:: Multi-step reaction with 3 steps

1: 1 h / Heating / reflux

2: copper(l) iodide; triethylamine; trimethylsilylacetylene / bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 1 h / 20 °C

3: 3-chloro-benzenecarboperoxoic acid / chloroform / 16 h / 20 °C

With copper(l) iodide; triethylamine; 3-chloro-benzenecarboperoxoic acid; trimethylsilylacetylene; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; chloroform;

Reference yield:

: 92671-70-0
acetic acid 2-bromopyridin-3-yl ester

: 181526-18-1
4-oxidofuro[3,2-b]pyridin-4-ium

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; triethylamine; trimethylsilylacetylene / bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 1 h / 20 °C

2: 3-chloro-benzenecarboperoxoic acid / chloroform / 16 h / 20 °C

With copper(l) iodide; triethylamine; 3-chloro-benzenecarboperoxoic acid; trimethylsilylacetylene; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; chloroform;