(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Base Information

Chemical Name:(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester
CAS No.:146404-54-8
Molecular Formula:C₃₇H₆₅NO₉Si
Molecular Weight:696.01
Hs Code.:

(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Synonyms:(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Suppliers and Price of (S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

There total 5 articles about (S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 146404-52-6
C₆₁H₁₀₃NO₁₄Si

: 146404-46-8
(3R,6S)-6-((3E,5E,7E)-(2S,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-trideca-3,5,7-trienyl)-3-methyl-tetrahydro-pyran-2-one

: 146404-54-8
(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 - -20 ℃; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(00)60797-9

Reference yield:

: 146404-49-1
C₆₃H₁₀₇NO₁₃Si₂

: 146404-54-8
(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / Pb(OAc)4 / 0 °C

2: 88 percent / LiHAl(OtBu)3 / tetrahydrofuran / 25 °C

3: LDA / tetrahydrofuran / -78 - -20 °C

With lead(IV) acetate; lithium tri-t-butoxyaluminum hydride; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)60797-9

Reference yield:

: 146404-50-4
C₆₃H₁₀₉NO₁₃Si₂

: 146404-54-8
(S)-1-Methoxyoxalyl-piperidine-2-carboxylic acid (E)-(1S,4R)-3-hydroxy-1-[(R)-2-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-1-methyl-ethyl]-4,6-dimethyl-7-oxo-hept-5-enyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / Pb(OAc)4 / 0 °C

2: 95 percent / TBAF/AcOH / tetrahydrofuran / 25 °C

3: LDA / tetrahydrofuran / -78 - -20 °C

With lead(IV) acetate; tetrabutyl ammonium fluoride; acetic acid; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)60797-9