TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE

Base Information

Chemical Name:TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE
CAS No.:181308-57-6
Molecular Formula:C12H21NO3
Molecular Weight:227.304
Hs Code.:2924299090
European Community (EC) Number:869-344-4,874-981-6
Mol file:181308-57-6.mol

Synonyms:TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE

Suppliers and Price of TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-ButylTrans-4-formylcyclohexylcarbamate
100mg
$ 65.00

TRC
tert-ButylTrans-4-formylcyclohexylcarbamate
50mg
$ 45.00

Matrix Scientific
tert-Butyl trans-4-formylcyclohexylcarbamate
1g
$ 215.00

Matrix Scientific
tert-Butyl trans-4-formylcyclohexylcarbamate
25g
$ 2365.00

Matrix Scientific
tert-Butyl trans-4-formylcyclohexylcarbamate
5g
$ 840.00

J&W Pharmlab
trans-(4-Formyl-cyclohexyl)-carbamicacidtert-butylester 97%
25g
$ 1590.00

J&W Pharmlab
trans-(4-Formyl-cyclohexyl)-carbamicacidtert-butylester 97%
1g
$ 98.00

J&W Pharmlab
trans-(4-Formyl-cyclohexyl)-carbamicacidtert-butylester 97%
5g
$ 398.00

Chemenu
tert-Butyltrans-4-formylcyclohexylcarbamate 95%
10g
$ 460.00

Biosynth Carbosynth
tert-Butyl trans-4-formylcyclohexylcarbamate
100 mg
$ 65.00

Total 26 raw suppliers

Chemical Property of TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE

Chemical Property:

Boiling Point:339.5±31.0 °C(Predicted)
PKA:12.33±0.40(Predicted)
PSA：55.40000
Density:1.04±0.1 g/cm3(Predicted)
LogP:2.65970
Water Solubility.:Slightly soluble in water.
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:227.15214353
Heavy Atom Count:16
Complexity:250

Purity/Quality:

99%, ^*data from raw suppliers

tert-ButylTrans-4-formylcyclohexylcarbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1CCC(CC1)C=O
Uses trans-4-(Boc-amino)cyclohexanecarboxaldehyde is used as a intermediate in pharmaceutical.

Technology Process of TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE

There total 10 articles about TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: trans-ethyl 4-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate

: 181308-57-6
trans-(4-formyl-cyclohexyl)-carbamic acid tert-butyl ester

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 ℃; Inert atmosphere;
DOI:10.1021/jm401318w

Reference yield: 94.0%

: 239074-29-4
trans (4-hydroxymethyl-cyclohexyl)-carbamic acid tert-butyl ester

: 181308-57-6
trans-(4-formyl-cyclohexyl)-carbamic acid tert-butyl ester

Guidance literature:: With sulfur trioxide pyridine complex; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; at 0 - 20 ℃;

Reference yield:

: 146307-51-9
methyl (1R,4R)-4-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate

: 181308-57-6
trans-(4-formyl-cyclohexyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: calcium chloride; sodium tetrahydroborate / tetrahydrofuran; ethanol / 20 °C

2: dichloromethane; dimethyl sulfoxide / 0.25 h / 20 °C

With sodium tetrahydroborate; calcium chloride; In tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide;