C₁₂H₈BrN₃

Base Information

• Chemical Name: C₁₂H₈BrN₃
• CAS No.: 1042224-71-4
• Molecular Formula: C₁₂H₈BrN₃
• Molecular Weight: 274.12
• Mol file: 1042224-71-4.mol

Synonyms:C₁₂H₈BrN₃

Chemical Property of C₁₂H₈BrN₃

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

3-(6-Bromopyridin-2-yl)imidazo[1,2-a]pyridine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₈BrN₃

There total 1 articles about C₁₂H₈BrN₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,6-Dibromopyridine (626-05-1) + 3-bromoimidazo[1,2-a]pyridine (4926-47-0) → C12H8BrN3 (1042224-71-4)

Guidance literature:

3-bromoimidazo[1,2-a]pyridine; With isopropylmagnesium chloride; magnesium; In tetrahydrofuran; at -78 ℃;

With tributyltin chloride; In tetrahydrofuran; at -78 - 20 ℃;

2,6-Dibromopyridine; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 20 - 66 ℃;

DOI:10.1016/j.bmcl.2008.04.039

Reference yield:

C12H8BrN3 (1042224-71-4) + tert-butyl (3S)-3-aminopiperidine-1-carboxylate (625471-18-3) → C22H27N5O2

Guidance literature:

at 150 ℃; Microwave irradiation;

DOI:10.1016/j.bmcl.2008.04.042

Reference yield:

C12H8BrN3 (1042224-71-4) + t-butyl piperidin-3-ylcarbamate (184637-48-7,172603-05-3) → C22H27N5O2

Guidance literature:

at 150 ℃; Microwave irradiation;

DOI:10.1016/j.bmcl.2008.04.042

upstream raw materials:

2,6-Dibromopyridine

3-bromoimidazo[1,2-a]pyridine

Downstream raw materials:

C₁₈H₁₄N₄

C₁₉H₁₃N₅

C₁₉H₁₃N₅