2,6-dihydroxyenzeneacetamide

Base Information

• Chemical Name: 2,6-dihydroxyenzeneacetamide
• CAS No.: 5663-54-7
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.164
• Mol file: 5663-54-7.mol

Synonyms:Homogentisinsaeureamid

Chemical Property of 2,6-dihydroxyenzeneacetamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-dihydroxyenzeneacetamide

There total 2 articles about 2,6-dihydroxyenzeneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

5-Hydroxy-2-coumaranone (2688-48-4) → Homogentisinsaeureamid (5663-54-7)

Guidance literature:

With ammonia; In tetrahydrofuran;

DOI:10.3987/com-98-8458

Reference yield:

→ Homogentisinsaeureamid (5663-54-7)

Guidance literature:

Lakton 2, NH3;

DOI:10.1016/S0040-4039(00)91047-5

Reference yield:

Homogentisinsaeureamid (5663-54-7) → indol-5-ol (1953-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: BH₃ / tetrahydrofuran

2: aq. NH₃, air / methanol

With ammonium hydroxide; air; borane; In tetrahydrofuran; methanol;

DOI:10.3987/com-98-8458

upstream raw materials:

5-Hydroxy-2-coumaranone

Downstream raw materials:

2,5-dihydroxyphenylethylamine

indol-5-ol