methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate

Base Information

• Chemical Name: methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate
• CAS No.: 96869-84-0
• Molecular Formula: C₂₈H₂₂NO₅P
• Molecular Weight: 483.46
• Mol file: 96869-84-0.mol

Synonyms:methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate

Chemical Property of methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate

There total 2 articles about methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

m-iodonitrobenzene (645-00-1) + carbon monoxide (201230-82-2) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate (96869-84-0)

Guidance literature:

With potassium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium dichloride; In 1,4-dioxane; at 100 ℃; for 12h; under 760.051 Torr; Autoclave;

DOI:10.1021/acs.orglett.6b02278

Reference yield: 92.0%

methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) + m-nitrobenzoic acid chloride (121-90-4) → methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate (96869-84-0)

Guidance literature:

In benzene; for 3h; Heating;

DOI:10.1055/s-1994-25402

Reference yield: 82.0%

methyl 3-(3-nitrophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate (96869-84-0) → methyl 3-(3-nitrophenyl)propiolate (7515-22-2)

Guidance literature:

at 250 ℃; for 0.333333h; under 1 Torr;

DOI:10.1055/s-1994-25402

upstream raw materials:

methyl (triphenylphosphoranylidene)acetate

m-nitrobenzoic acid chloride

m-iodonitrobenzene

carbon monoxide

Downstream raw materials:

3-(3-nitrophenyl)propynoic acid

methyl 3-(3-nitrophenyl)propiolate