dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Base Information

Chemical Name:dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate
CAS No.:866885-37-2
Molecular Formula:C₅₁H₆₃O₁₂PSi
Molecular Weight:927.113
Hs Code.:

Synonyms:dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Suppliers and Price of dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

There total 7 articles about dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Carbonic acid (2R,3R,4R,5R,6S)-3,4-bis-benzyloxy-6-(dibutoxy-phosphoryloxy)-5-hydroxy-tetrahydro-pyran-2-ylmethyl ester 2-(dimethyl-naphthalen-2-ylmethyl-silanyl)-ethyl ester

: 98-88-4
benzoyl chloride

: 866885-37-2
dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Guidance literature:: With dmap; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1081/CAR-200067008

Reference yield:

: 866885-19-0
dimethyl(2-naphthylmethyl)vinylsilane

: 866885-37-2
dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 6 steps

1.1: 9-borabicyclo[3.3.1]nonane / tetrahydrofuran / 1 h / 20 °C

1.2: 58 percent / hydrogen peroxide; sodium hydroxide / ethanol; H₂O / 1 h / Heating

2.1: 63 percent / diethyl ether; toluene / 2.5 h / -15 - 20 °C

3.1: 98 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 15 h / 20 °C

4.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / 0 °C

5.1: CH₂Cl₂ / 0.5 h / -78 °C

6.1: 0.290 g / 4-(dimethylamino)pyridine / CH₂Cl₂ / 3 h / 0 - 20 °C

With dmap; 3,3-dimethyldioxirane; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; diethyl ether; dichloromethane; acetone; toluene;
DOI:10.1081/CAR-200067008

Reference yield:

: 866885-20-3
2-[dimethyl(2-naphthylmethyl)silyl]ethanol

: 866885-37-2
dibutyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 5 steps

1: 63 percent / diethyl ether; toluene / 2.5 h / -15 - 20 °C

2: 98 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 15 h / 20 °C

3: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / 0 °C

4: CH₂Cl₂ / 0.5 h / -78 °C

5: 0.290 g / 4-(dimethylamino)pyridine / CH₂Cl₂ / 3 h / 0 - 20 °C

With dmap; 3,3-dimethyldioxirane; In diethyl ether; dichloromethane; acetone; toluene;
DOI:10.1081/CAR-200067008