3-Chloro-1-(2-hydroxyphenyl)-1-propanone

Base Information

• Chemical Name: 3-Chloro-1-(2-hydroxyphenyl)-1-propanone
• CAS No.: 35999-21-4
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.622
• DSSTox Substance ID: DTXSID801275844
• Mol file: 35999-21-4.mol

Synonyms:3-Chloro-1-(2-hydroxyphenyl)-1-propanone;35999-21-4;3-chloro-1-(2-hydroxyphenyl)propan-1-one;3-Chloro-2'-hydroxypropiophenone;DTXSID801275844;AC5995;MFCD00511236;CS-12318;SY046373;A913564

Chemical Property of 3-Chloro-1-(2-hydroxyphenyl)-1-propanone

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 184.0291072
• Heavy Atom Count: 12
• Complexity: 159

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-2'-hydroxypropiophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)CCCl)O

Technology Process of 3-Chloro-1-(2-hydroxyphenyl)-1-propanone

There total 3 articles about 3-Chloro-1-(2-hydroxyphenyl)-1-propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-3-chloropropiophenone (938-67-0) → 3-chloro-1-(2-hydroxy-phenyl)-propan-1-one (35999-21-4)

Guidance literature:

With hydrogenchloride; In titanium tetrachloride;

Reference yield:

3-chloropropionic acid phenyl ester (24552-27-0) → 3-chloro-1-(2-hydroxy-phenyl)-propan-1-one (35999-21-4)

Guidance literature:

With aluminium trichloride; at 100 ℃;

Reference yield:

→ 3-chloro-1-(2-hydroxy-phenyl)-propan-1-one (35999-21-4)

Guidance literature:

<2-Hydroxy-phenyl>-vinyl-keton u. HCl;

upstream raw materials:

3-chloropropionic acid phenyl ester

2-hydroxy-3-chloropropiophenone