2-(3-ethoxyphenyl)acetic acid

Base Information

• Chemical Name: 2-(3-ethoxyphenyl)acetic acid
• CAS No.: 72775-83-8
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.203
• Hs Code.: 2918999090
• Mol file: 72775-83-8.mol

Synonyms:3-Ethoxyphenylacetic acid

Chemical Property of 2-(3-ethoxyphenyl)acetic acid

Chemical Property:

• Melting Point: 92-93 °C
• Boiling Point: 318.0±17.0 °C(Predicted)
• PKA: 4.19±0.10(Predicted)
• Density: 1.144±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

(3-Ethoxyphenyl)aceticacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (3-Ethoxyphenyl)acetic acid

Technology Process of 2-(3-ethoxyphenyl)acetic acid

There total 5 articles about 2-(3-ethoxyphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl 3-ethoxyphenylacetate (139988-02-6) → 3-Ethoxyphenylacetic acid (72775-83-8)

Guidance literature:

methyl 3-ethoxyphenylacetate; With sodium hydroxide; ethanol; water; at 20 ℃; for 0.5h;

With hydrogenchloride; In ethanol; water;

Reference yield:

3-hydroxy-benzeneacetic acid, methyl ester (42058-59-3) → 3-Ethoxyphenylacetic acid (72775-83-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, RT, overnight

2: 86 percent / 6.25 N NaOH / methanol / Ambient temperature

With sodium hydroxide; sodium hydride; In methanol;

DOI:10.1021/jm00068a004

Reference yield:

m-hydroxyphenylacetic acid (621-37-4) → 3-Ethoxyphenylacetic acid (72775-83-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 150 °C

2: sodium hydroxide / ethanol; water / 2 h / 100 °C

With potassium carbonate; sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2013.10.039

upstream raw materials:

1-(3-ethoxyphenyl)ethan-1-one

methyl 3-ethoxyphenylacetate

3-hydroxy-benzeneacetic acid, methyl ester

m-hydroxyphenylacetic acid

Downstream raw materials:

N-[2-(2,5-Dimethoxy-phenyl)-ethyl]-2-(3-ethoxy-phenyl)-acetamide

(3-Ethoxy-phenyl)-acetyl chloride

2-(3-ethoxyphenylacetylamino)benzamide

2-(3,4-diethoxyphenyl)-N-(4-phenylthiazol-2-yl)acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 72775-83-8 2-(3-ethoxyphenyl)acetic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send