methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Base Information

Chemical Name:methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate
CAS No.:1428548-51-9
Molecular Formula:C₂₄H₂₄N₄O₇
Molecular Weight:480.477
Hs Code.:

Synonyms:methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Suppliers and Price of methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

There total 7 articles about methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1428548-50-8
2-[(benzyloxy)methyl]-N-[bis(4-methoxyphenyl)methyl]-4-hydroxypyrimidine-5-carboxamide

: 1428548-51-9
methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 20 ℃;

Reference yield:

: 1428548-50-8
2-[(benzyloxy)methyl]-N-[bis(4-methoxyphenyl)methyl]-4-hydroxypyrimidine-5-carboxamide

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 1428548-51-9
methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 20 ℃;

Reference yield:

: 1428548-41-7
2-((benzyloxy)methyl)-4-hydroxypyrimidine-5-carboxylic acid

: 1428548-51-9
methyl 2-[5-{[bis(4-methoxyphenyl)methyl]carbamoyl}-4-hydroxypyrimidine-2-carboxamido]acetate

Guidance literature:: Multi-step reaction with 5 steps

1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide; N,N-dimethyl-formamide / 20 °C

2: palladium on activated charcoal; ammonium formate / methanol / Reflux

3: Dess-Martin periodane / dichloromethane / 1 h / 20 °C

4: sodium chlorite; sodium hydrogenphosphate dodecahydrate / tert-butyl alcohol / 2 h / 20 °C

5: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 20 °C

With sodium chlorite; sodium hydrogenphosphate dodecahydrate; palladium on activated charcoal; ammonium formate; Dess-Martin periodane; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; tert-butyl alcohol;