(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid

Base Information

• Chemical Name: (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid
• CAS No.: 1033038-24-2
• Molecular Formula: C₁₃H₁₀N₄O₂S
• Molecular Weight: 286.314
• Mol file: 1033038-24-2.mol

Synonyms:(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid

Chemical Property of (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid

There total 3 articles about (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

ethyl-2-(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)acetate (1033038-23-1) → (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid (1033038-24-2)

Guidance literature:

ethyl-2-(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)acetate; With sodium hydroxide; In ethanol; for 0.25h; Reflux;

With hydrogenchloride; In water;

DOI:10.1002/ardp.200700181

Reference yield: 81.0%

6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione (66129-30-4) + chloroacetic acid ethyl ester (105-39-5) → (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid (1033038-24-2)

Guidance literature:

6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione; chloroacetic acid ethyl ester; With sodium hydroxide; In ethanol; for 0.333333h; Reflux;

With hydrogenchloride; In water;

DOI:10.1002/ardp.200700181

Reference yield: 75.0%

6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione (66129-30-4) + chloroacetic acid (79-11-8) → (6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)-acetic acid (1033038-24-2)

Guidance literature:

6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione; chloroacetic acid; With sodium hydroxide; In ethanol; for 2h; Reflux;

With hydrogenchloride; In water;

DOI:10.1002/ardp.200700181

upstream raw materials:

6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione

chloroacetic acid ethyl ester

chloroacetic acid

ethyl-2-(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)acetate